References

glaucoma

Национальный журнал Глаукома

National Journal glaucoma

2078-41042311-6862

Federal State Budgetary Institution of Science “Krasnov Research Institute of Eye Diseases”

glaucoma-119

Research Article

ОБЗОР ЛИТЕРАТУРЫ

REVIEW OF LITERATURE

Оптическая когерентная томография в диагностике глаукомной оптиконейропатии. Часть 2

Optical coherence tomography in glaucoma optic neuropathy diagnostics. Part 2

Курышева

Н. И.

Kurysheva

N. I.

e-natalia@list.ru

Центр офтальмологии ФМБА России; Клиническая больница № 86РоссияOphthalmological Center of the Federal Medical and Biological Agency; Clinical Hospital No. 86Russian Federation

2016

17012017

1536070

2017

Курышева Н.И.

Kurysheva N.I.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.glaucomajournal.ru/jour/article/view/119

Метод спектральной оптической когерентной томографии (ОКТ, SD-OCT) на сегодня становится основным в ранней диагностике глаукомы. Толщина слоя нервных волокон перипапиллярной сетчатки (RNFL) представляется наиболее надежным клиническим параметром в этом плане. Однако последние данные литературы свидетельствуют о важной роли исследования внутренних слоев макулы, в частности параметров ганглиозного комплекса сетчатки (GCC), объема фокальных (FLV) и глобальных потерь (GLV) для раннего выявления глаукомы. В этом плане исследование ДЗН и решетчатой мембраны склеры пока отстают по диагностической ценности от упомянутых выше показателей. В то же время в центре внимания исследователей - минимальная ширина неврального ободка (minimum rim width, MRW), - новый перспективный параметр в ранней диагностике глаукомы. Применение SD-OCT для определения прогрессирования глаукомы изучено достаточно широко, но до сих пор нет четких клинических рекомендаций. В обзоре приведен сравнительный анализ рассматриваемых методов как для ранней диагностики заболевания, так и для наблюдения в динамике. Отмечены ограничения метода ОКТ в диагностике глаукомы. Показаны преимущества комбинации методов структурной и функциональной оценки.

Today, the method of spectral optical coherence tomography (SD-OCT) is gaining the main role in the early diagnosis of glaucoma. The thickness of the peripapillary retinal nerve fiber layer (RNFL) is the most reliable clinical parameter in this regard. However, recent literature data suggests an important role of the study of the macular inner layers, in particular the parameters of ganglion cell complex (GCC), focal loss volume (FLV) and global loss volume (GLV) for the early glaucoma detection. In this regard, the study of the ONH and lamina cribrosa is of less diagnostic value. At the same time researchers are focused on minimum width of the neural rim (minimum rim width, MRW), - a promising new option in early glaucoma diagnostics. The application of SD-OCT for determining glaucoma progression is still under development. The review provides a comparative analysis of these methods for early diagnosis and monitoring of the disease. Limitations of OCT in glaucoma diagnostics are noted. The advantages of combining structural and functional evaluation methods in glaucoma diagnostics are also shown.

primary open-angle glaucomaGCCSD-OCTchoroidal thicknessRNFLlamina cribrosa

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The authors declare that there are no conflicts of interest present.