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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">glaucoma</journal-id><journal-title-group><journal-title xml:lang="ru">Национальный журнал Глаукома</journal-title><trans-title-group xml:lang="en"><trans-title>National Journal glaucoma</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-4104</issn><issn pub-type="epub">2311-6862</issn><publisher><publisher-name>Federal State Budgetary Institution of Science “Krasnov Research Institute of Eye Diseases”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25700/NJG.2020.01.07</article-id><article-id custom-type="elpub" pub-id-type="custom">glaucoma-274</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW OF LITERATURE</subject></subj-group></article-categories><title-group><article-title>Селективная лазерная трабекулопластика как стартовый метод лечения первичной открытоугольной глаукомы</article-title><trans-title-group xml:lang="en"><trans-title>Selective laser trabeculoplasty as the initial treatment of primary open-angle glaucoma</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Еричев</surname><given-names>В. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Erichev</surname><given-names>V. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Еричев Валерий Петрович, д.м.н., профессор, руководитель отдела глаукомы</p></bio><bio xml:lang="en"><p>Med.Sc.D., Professor, Head of Glaucoma Department</p></bio><email xlink:type="simple">erichev@reic.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рагозина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ragozina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ординатор</p></bio><bio xml:lang="en"><p>resident</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «НИИ глазных болезней»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Research Institute of Eye Diseases</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>20</day><month>04</month><year>2020</year></pub-date><volume>19</volume><issue>1</issue><fpage>47</fpage><lpage>54</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Еричев В.П., Рагозина Е.А., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Еричев В.П., Рагозина Е.А.</copyright-holder><copyright-holder xml:lang="en">Erichev V.P., Ragozina E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.glaucomajournal.ru/jour/article/view/274">https://www.glaucomajournal.ru/jour/article/view/274</self-uri><abstract><p>Селективная лазерная трабекулопластика (СЛТ) является сравнительно молодым методом снижения внутриглазного давления у больных первичной открытоугольной глаукомой (ПОУГ). К основным преимуществам СЛТ относят ее безопасность и эффективность. Во всем мире лазерные методы являются второй линией лечения глаукомы, которое в большинстве случаев начинают с подбора местных гипотензивных средств. Известно, что активные компоненты глазных капель и содержащиеся в них консерванты вызывают нежелательные побочные эффекты. Данная проблема особенно актуальна у пациентов с глаукомой из-за необходимости в пожизненной терапии с момента постановки диагноза. Кроме того, механизмы взаимодействия антиглаукомных препаратов и лекарств, принимаемых пациентами по поводу общих заболеваний, остаются не до конца изученными. В связи с вышеуказанными проблемами вопрос о возможности проведения СЛТ пациентам с впервые выявленной ПОУГ на сегодняшний день остается актуальным. В нашем обзоре мы сравнили методы селективной лазерной трабекулопластики и медикаментозной терапии, анализируя имеющуюся информацию относительно показаний, противопоказаний, осложнений, эффективности методов, качества жизни пациентов и экономических аспектов</p></abstract><trans-abstract xml:lang="en"><p>Selective laser trabeculoplasty (SLT) is a relatively new method of intraocular pressure lowering in patients with primary open-angle glaucoma (POAG). The main advantages of SLT are its safety and effectiveness. Laser methods are considered to be the second line of glaucoma treatment worldwide. Hyportensive drugs are usually used as the initial method for glaucoma patients. It is common knowledge that preservatives and active components of eye drops usually cause adverse effects. This problem is especially relevant in patients with POAG due to the need for lifelong therapy starting from the moment of proving the diagnosis. In addition, the mechanisms of interaction between antiglaucoma drugs and medications for extraocular diseases remain unclear. Therefore, the question of initial SLT in patients with newly diagnosed POAG remains essentially important. In our review we compared the methods of selective laser trabeculoplasty and drug therapy in glaucoma treatment, analyzing available information regarding indications, contraindications, complications and effectiveness of the methods, patients’ quality of life and economic aspects.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>первичная открытоугольная глаукома</kwd><kwd>селективная лазерная трабекулопластика</kwd><kwd>гипотензивная эффективность</kwd><kwd>внутриглазное давление</kwd></kwd-group><kwd-group xml:lang="en"><kwd>primary open-angle glaucoma</kwd><kwd>selective laser trabeculoplasty</kwd><kwd>hypotensive efficacy</kwd><kwd>intraocular pressure</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Quigley H.A. Clinical trials for glaucoma neuroprotection are not impossible. 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