glaucomaНациональный журнал ГлаукомаNational Journal glaucoma2078-41042311-6862Federal State Budgetary Institution of Science “Krasnov Research Institute of Eye Diseases”10.25700/NJG.2020.03.10glaucoma-293Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEW OF LITERATUREИзменения глазной поверхности после различных видов антиглаукомных операцийOcular surface changes after filtration surgeryНагорноваЗ. М.NagornovaZ. M.

Нагорнова Зоя Михайловна, аспирант, ассистент кафедры оториноларингологии и офтальмологии 

153012, Иваново, пр. Шереметевский, 8

Assistant Professor

8 Sheremetevskiy av., Ivanovo, 153012

myxazai@mail.ruСелезневА. В.SeleznevA. V.

Кандидат медицинских наук, доцент кафедры оториноларингологии и офтальмологии

153012, Иваново, пр. Шереметевский, 8

Ph.D., Associate Professor

8 Sheremetevskiy av., Ivanovo, 153012

КуроедовА. В.KuroyedovA. V.

Доктор медицинских наук, начальник отделения ЦВКГ им.П.В. Мандрыка, профессор кафедры офтальмологии лечебного факультета им. акад. А.П. Нестерова РНИМУ им. Н.И. Пирогова

107014, Москва, ул. Б. Оленья, 8А; 117997, Москва, ул. Островитянова, 1;

Med.Sc.D., Head of Ophthalmology Department, Professor 

8а Bol’shaya Olen’ya st., Moscow, 107014; 1 Ostrovitianov st., Moscow, 117997 

ГазизоваИ. Р.GazizovaI. R.

Доктор медицинских наук, заведующая отделением 

197376, Санкт-Петербург, ул. Академика Павлова, 12

Med.Sc.D., Head of Ophthalmology Department 

12 Academy Pavlov st., Saint-Petersburg, 197376

БорисоваЕ. А.BorisovaE. A.

Заведующая детским офтальмологическим отделением

153040, Иваново, ул. Любимова, 1

Head of Ophthalmology Department 

1 Lubimova st., Ivanovo, 153000

ФГБОУ ВО «Ивановская государственная медицинская академия» Минздрава РФРоссияIvanovo State Medical AcademyRussian FederationФКУ «ЦВКГ им. П.В. Мандрыка» Минобороны РФ; ФГАОУ ВО «РНИМУ им. Н.И. Пирогова» Минздрава РФРоссияMandryka Military Central Clinical Hospital; Pirogov Russian National Research Medical UniversityRussian FederationФедеральное государственное научное учреждение «Институт экспериментальной медицины» РАНРоссияNorth-West Federal Medical and Research CenterRussian FederationОБУЗ «Ивановская областная клиническая больница»,РоссияPublic Clinical Hospital of IvanovoRussian Federation2020091020201938996Copyright © Нагорнова З.М., Селезнев А.В., Куроедов А.В., Газизова И.Р., Борисова Е.А., 20202020Нагорнова З.М., Селезнев А.В., Куроедов А.В., Газизова И.Р., Борисова Е.А.Nagornova Z.M., Seleznev A.V., Kuroyedov A.V., Gazizova I.R., Borisova E.A.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.glaucomajournal.ru/jour/article/view/293

В данном обзоре обобщены результаты исследований, посвященных анализу состояния глазной поверхности у пациентов с первичной открытоугольной глаукомой (ПОУГ) после антиглаукомных операций (преимущественно синустрабекулэктомии), а также влияние данных изменений на качество жизни. Уровень внутриглазного давления (ВГД) является единственным модифицируемым фактором в лечении ПОУГ. Как правило, в начале лечения ПОУГ применяют местные гипотензивные препараты, компоненты и действующие вещества которых могут влиять на глазную поверхность, зачастую приводя к ятрогенному синдрому «сухого глаза» (ССГ). Симптомы ССГ ухудшают качество жизни пациентов и снижают приверженность лечению, что, в свою очередь, негативно влияет на результаты лечения. Стоит отметить, что продвинутые стадии заболевания нуждаются в хирургическом лечении, которое, несмотря на малый временной интервал в сравнении с ежедневной местной терапией, также оказывает воздействие на состояние глазной поверхности.

This review summarizes the results of studies dedicated to analyzing the ocular surface condition and the patients’ quality of life after filtration surgery (mainly sinus trabeculectomy). Intraocular pressure is the only modifiable factor in the treatment of primary open-angle glaucoma (POAG). Usually POAG treatment starts with antihypertensive eye drops, the components and active substances of which can affect the ocular surface, and lead to iatrogenic dry eye syndrome (DES). The symptoms of DES impair the quality of life of glaucoma patients and reduce adherence to treatment. It is worth noting that advanced stages of the disease require surgical treatment, which also effects the ocular surface.

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The authors declare that there are no conflicts of interest present.