glaucomaНациональный журнал ГлаукомаNational Journal glaucoma2078-41042311-6862Federal State Budgetary Institution of Science “Krasnov Research Institute of Eye Diseases”10.25700/NJG.2021.01.06glaucoma-315Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEW OF LITERATUREОКТ-ангиография в оценке структурного состояния центральной зоны сетчатки в условиях индуцированной гипотонииOCT angiography in the assessment of central retinal structure under induced hypotensionЕричевВ. П.ErichevV. P.

  Еричев Валерий Петрович, д.м.н., профессор, руководитель отдела глаукомы 

119021, Москва, ул. Россолимо, 11А, Б

 Dr. Sci. (Med.), Professor, Head of the Glaucoma Department 

11A Rossolimo St., Moscow, 119021

erichev@reic.ruРагозинаЕ. А.RagozinaE. A.

 младший научный сотрудник отдела глаукомы 

119021, Москва, ул. Россолимо, 11А, Б

 Junior Researcher at the Glaucoma Department 

11A Rossolimo St., Moscow, 119021

ФГБНУ «Научно-исследовательский институт глазных болезней»РоссияResearch Institute of Eye DiseasesRussian Federation2021230320212014754Copyright © Еричев В.П., Рагозина Е.А., 20212021Еричев В.П., Рагозина Е.А.Erichev V.P., Ragozina E.A.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.glaucomajournal.ru/jour/article/view/315

На сегодняшний день единственным доступным способом лечения первичной открытоугольной глаукомы является снижение внутриглазного давления медикаментозными, лазерными или хирургическими методами. Однако в патогенезе глаукомы важную роль наравне с механическим также играет сосудистый фактор, воздействие на который в перспективе может стать новым способом замедления развития хронической глаукомной оптиконейропатии. Оптическая когерентная томография ангиография (ОКТ-А) является сравнительно молодым методом изучения микроциркуляции сетчатки и диска зрительного нерва и имеет множество преимуществ в сравнении с другими методами исследования гемодинамики глаза — неинвазивность, воспроизводимость и повторяемость результатов. Известно, что при глаукоме происходят изменения показателей гемодинамики диска зрительного нерва, перипапиллярной сетчатки и макулярной области. В нашем обзоре мы проводим анализ имеющихся данных о влиянии антиглаукомных операций и, как следствие, индуцированной гипотонии на ОКТ-А параметры микроциркуляции центральной зоны сетчатки.

Today the only available treatment option for patients with primary open-angle glaucoma is lowering intraocular pressure with medication, laser or surgical procedures. However, besides the mechanical factor, pathogenesis of glaucoma also involves the vascular factor, which in the future may become a new treatment target for slowing chronic neurodegeneration. Optical coherence tomography angiography (OCT-A) is a relatively new method for studying the microcirculation in the retina and optic nerve head. It has many advantages over other methods used for studying ocular blood flow including non-invasiveness, reproducibility and repeatability of results. Glaucoma is known to affect the hemodynamic parameters of the optic nerve head, peripapillary retina and macular region. This review analyzes available data on the effects of glaucoma surgeries and, consequently, induced hypotension on OCT-A parameters of microcirculation in the macular region.

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The authors declare that there are no conflicts of interest present.