glaucomaНациональный журнал ГлаукомаNational Journal glaucoma2078-41042311-6862Federal State Budgetary Institution of Science “Krasnov Research Institute of Eye Diseases”10.53432/2078-4104-2022-21-3-72-84glaucoma-403Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEW OF LITERATUREОб оптимальных значениях «целевого» уровня внутриглазного давленияOn the optimal values of «target» intraocular pressureКацМ. Д.KatsM. D.

Михаил Дмитриевич Кац, врач-офтальмоло, аспирант

ГБУЗ ГКБ № 15 им. О. М. Филатова

кафедра офтальмологии

111539

ул. Вешняковская, 23

117997

ул. Островитянова, 1

Москва

Ophthalmologist, postgraduate student

Academic Department of Ophthalmology

111539

23 Veshnyakovskaya St.

117997

1 Ostrovityanova St.

Moscow

katzm@mail.ruКуроедовА. В.KuroyedovA. V.

д. м. н., начальник отделения, профессор

офтальмологическое отделение

кафедра офтальмологии

107014

ул. Большая Оленья, 8А

117997

ул. Островитянова, 1

Москва

Dr. Sci. (Med.), Head of the Department, Professor

Ophthalmology Department

Academic Department of Ophthalmology

107014

8A Bolshaya Olenya St.

117997

1 Ostrovityanova St.

Moscow

ДЗМ; ФГАОУ ВО РНИМУ им. Н. И. ПироговаРоссияMunicipal Clinical Hospital No. 15 named after O. M. Filatov; Pirogov Russian National Research Medical UniversityRussian FederationФКУ ЦВКГ им. П. В. Мандрыка; ФГАОУ ВО РНИМУ им. Н. И. ПироговаРоссияMandryka Central Clinical Military Hospital; Pirogov Russian National Research Medical UniversityRussian Federation2022300820222137284Copyright © Кац М.Д., Куроедов А.В., 20222022Кац М.Д., Куроедов А.В.Kats M.D., Kuroyedov A.V.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.glaucomajournal.ru/jour/article/view/403

   Современные мировые статистические данные свидетельствуют, что глаукома является основным заболеванием, приводящим к необратимой слепоте. Это обстоятельство обуславливает неослабевающий интерес к поиску новых методов быстрой и точной диагностики данного заболевания. На сегодняшний день снижение уровня внутриглазного давления (ВГД) является единственной доказанной стратегией для замедления прогрессирования глаукомной оптической нейропатии. Достижение т. н. «целевого» ВГД является задачей любой эффективной антиглаукомной терапии. Однако, как показывает практика, компенсация ВГД не всегда приводит к стабилизации глаукомного процесса. Концепции определения «целевого» уровня ВГД подразумевают процентное снижение; рассчитанное на основе формул или заранее определенное значение; диапазон значений офтальмотонуса. Однако ни одна из этих стратегий не была выбрана в качестве ведущей. Определение «давления цели» многогранно и требует внимания ко многим различным факторам. Кроме того, постоянно развивается понимание, как именно уровень ВГД влияет на развитие глаукомы. В данном обзоре мы обобщаем данные о понятии «целевого» уровня ВГД, а также о различных концепциях по его достижению.

   Current statistics show that glaucoma is the main cause of irreversible blindness worldwide. This fact generates continued interest in the search for new methods of rapid and accurate diagnosis of the disease. Presently, reducing the level of intra-ocular pressure (IOP) is the only proven strategy for slowing the progression of glaucomatous optic neuropathy. As such, achieving the so-called «target» pressure is the aim of any effective anti-glaucoma therapy. However, as practice shows, compensation of IOP does not always lead to stabilization of glaucoma progression. The concept of determining the «target» level of IOP implies a percentage decrease calculated by formulas, or a predetermined value, or a range of values. However, none of these strategies are considered as the leading one. The definition of «target pressure» is multifaceted and requires attention to many different factors. In addition, the understanding of how the level of IOP affects the progression of glaucoma is constantly evolving. In this review we summarize the data on the concept of «target» IOP, as well as on various concepts of achieving it.

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The authors declare that there are no conflicts of interest present.