glaucomaНациональный журнал ГлаукомаNational Journal glaucoma2078-41042311-6862Federal State Budgetary Institution of Science “Krasnov Research Institute of Eye Diseases”10.53432/2078-4104-2023-22-4-3-14glaucoma-442Research ArticleОРИГИНАЛЬНЫЕ СТАТЬИORIGINAL ARTICLESСравнительное исследование эффективности ленсэктомии и периферической лазерной иридотомии при первичном закрытии угла передней камеры глазаComparative study of the efficacy of lens extraction and laser peripheral iridotomy in primary anterior chamber angle closurehttps://orcid.org/0000-0002-2265-6671КурышеваН. И.KuryshevaN. I.

д.м.н., профессор, заведующая кафедрой глазных болезней, Медико-биологический университет инноваций и непрерывного образования ФГБУ ГНЦ РФ «Федеральный биофизический центр им. А.И. Бурназяна» ФМБА России; руководитель консультативно-диагностического отдела, Консультативно-диагностический отдел Центра офтальмологии ФМБА России, ФГБУ ГНЦ РФ «ФМБЦ им. А.И. Бурназяна» ФМБА

123098, Москва, ул. Живописная, 46, корп. 8

123098, Москва, ул. Гамалеи, 15

Professor, Head of the Academic Department of Ophthalmology, Medical Biological University of Innovations and Continuing Education of the State Research Center —  Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency; Head of the Consultative and Diagnostic Department, Ophthalmological Center of the State Research Center — Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency

46-8 Zhivopisnaya St., Moscow, 123098

15 Gamalei St., Moscow, 123098

e-natalia@list.ruhttps://orcid.org/0000-0002-0146-8284РодионоваО. Е.RodionovaO. Ye.

д.ф.‐м.н., главный научный сотрудник

Москва, ул. Косыгина, 4

Dr. Sci. (Phys. and Math)., Chief Researcher

4 Kosygina St., Moscow, 119991

oxana.rodionova@gmail.comhttps://orcid.org/0000-0001-7402-4011ПомеранцевА. Л.PomerantsevA. L.

д.ф.‐м.н., главный научный сотрудник

Москва, ул. Косыгина, 4

Dr. Sci. (Phys. and Math)., Chief Researcher

4 Kosygina St., Moscow, 119991

alexey.pomerantsev@gmail.comhttps://orcid.org/0000-0002-7163-4858ШароваГ. А.SharovaG. A.

Шарова Галина Аркадьевна, к.м.н., ассистент кафедры глазных болезней, Медико-биологический университет инноваций и непрерывного образования ФГБУ ГНЦ РФ «Федеральный биофизический центр им. А.И. Бурназяна» ФМБА России; заведующая диагностическим офтальмологическим отделением, ООО «Глазная клиника доктора Беликовой»

123098, Москва, ул. Живописная, 46, корп. 8

105118, Москва, пр. Буденного, 26, к. 2

Cand. Sci. (Med.), Assistant Professor at the Academic Department of Ophthalmology, Medical Biological University of Innovations and Continuing Education of the State Research Center —  Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency; Head of the Diagnostic Ophthalmology Department, OOO Glaznaya Klinika Doktora Belikovoy

46-8 Zhivopisnaya St., Moscow, 123098

26/2 Budenny Av., Moscow, 105118

galina.shar@mail.ruМедико-биологический университет инноваций и непрерывного образования ФГБУ ГНЦ РФ «Федеральный биофизический центр им. А.И. Бурназяна» ФМБА России; Консультативно-диагностический отдел Центра офтальмологии ФМБА России, ФГБУ ГНЦ РФ «ФМБЦ им. А.И. Бурназяна» ФМБАРоссияMedical Biological University of Innovations and Continuing Education of the State Research Center — Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency; Ophthalmological Center of the State Research Center — Burnasyan Federal Medical Biophysical Center of Federal Medical Biological AgencyRussian FederationФГБУН «Федеральный исследовательский центр химической физики им. Н.Н. Семенова» Российской академии наукРоссияN.N. Semenov Federal Research Center for Chemical Physics, Russian Academy of SciencesRussian FederationМедико-биологический университет инноваций и непрерывного образования ФГБУ ГНЦ РФ «Федеральный биофизический центр им. А.И. Бурназяна» ФМБА России; ООО «Глазная клиника доктора Беликовой»РоссияMedical Biological University of Innovations and Continuing Education of the State Research Center — Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency; OOO Glaznaya Klinika Doktora BelikovoyRussian Federation202318042023224314Copyright © Курышева Н.И., Родионова О.Е., Померанцев А.Л., Шарова Г.А., 20232023Курышева Н.И., Родионова О.Е., Померанцев А.Л., Шарова Г.А.Kurysheva N.I., Rodionova O.Y., Pomerantsev A.L., Sharova G.A.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.glaucomajournal.ru/jour/article/view/442ЦЕЛЬ

ЦЕЛЬ. Сравнить анатомо-функциональную эффективность ленсэктомии (ЛЭ) и периферической лазерной иридотомии (ПЛИТ) у пациентов с первичным закрытием угла передней камеры (ПЗУ).

МЕТОДЫ

МЕТОДЫ. Проспективное исследование включало 120 пациентов в возрасте от 41 до 80 лет (60 глаз — ПЗУ, 30 глаз с подозрением на первичное закрытие угла [ППЗУ], 30 глаз без офтальмопатологии). На 30 глазах с ПЗУ выполнена ЛЭ с имплантацией интраокулярной линзы, на 30 — ПЛИТ. Всем обследуемым проведена оптическая когерентная томография Swept Source (SS-OCT). Анализируемые параметры включали: сфероэквивалент (СЭ), остроту зрения с коррекцией и без, внутриглазное давление (ВГД), степень открытия угла по Шафферу, прозрачность хрусталика, гониосинехии, толщину хориоидеи в макуле, длину передне-задней оси глаза (ПЗО), глубину передней камеры (ГПК), высоту свода хрусталика (LV), кривизну радужки (ICurv), толщину радужки в 750 мкм от склеральной шпоры (IT750), дистанцию открытия угла передней камеры (УПК) (AOD500, AOD750), площадь иридотрабекулярного пространства (TISA500, TISA750). Наряду со стандартными методами описательной статистики использовались методы машинного обучения, включая метод одноклассовой классификации DD-SIMCA.

РЕЗУЛЬТАТЫ

РЕЗУЛЬТАТЫ. Каждый третий глаз с ПЗУ после ЛЭ дости гал значений контрольной группы по совокупности изучаемых параметров (специфичность по DD-SIMCA 0,67), чего не наблюдалось в глазах после ПЛИТ (специфичность по DD-SIMCA 1,0), а вероятность попадания в контрольную группу оценивается как 0,01. После ЛЭ все параметры УПК достоверно не отличались от нормы (все p>0,05), а ГПК, ICurv даже превысили норматив (p=0,000). После ПЛИТ наблюдалось углубление ГПК (с 2,34±0,28 мм до 2,36±0,280 мм, p=0,000) и уменьше ние LV (c 0,864±0,120 мкм до 0,843±0,110 мкм, p=0,000), однако сопоставимость с контролем была достигнута только по ICurv (p=1,000). После ЛЭ при ПЗУ все показатели, включая остроту зрения без коррекции, СЭ, ГПК, LV, профиль радужки, размеры УПК по Шафферу и параметры AOD500, AOD750, TISA500, TISA750 в верхних и нижних секторах имели преимущества перед таковыми при ППЗУ без лечения (р<0,05). После ПЛИТ достигнуто также улучшение ряда параметров по сравнению с ППЗУ: ICurv, УПК по Шафферу, AOD500, AOD750, TISA500, TISA750 в верхних секторах и AOD500 в нижнем секторе (р><0,05).

ЗАКЛЮЧЕНИЕ

ЗАКЛЮЧЕНИЕ. Эффективность ЛЭ при ПЗУ выше, чем ПЛИТ, что обусловлено лучшими постоперационными топографическим параметрами передней камеры и более низким ВГД. Оба метода лечения, особенно ЛЭ, улучшают указанные параметры по сравнению с ППЗУ. ЛЭ — метод выбора лечения ранних стадий ПЗУ передней камеры.

PURPOSE

PURPOSE. To compare the anatomical and functional effectiveness of lensectomy (LE) and laser peripheral iridotomy (LPI) in patients with primary anterior chamber angle closure.

METHODS

METHODS. This prospective study included 120 patients aged 41 to 80 years (60 eyes — primary angle closure (PAC), 30 — primary angle closure suspects (PACs), 30 eyes — without ophthalmic pathology). 30 PAC eyes were treated using LE with intraocular lens implantation, and 30 eyes with LPI. All subjects underwent swept source optical coherence tomography (SS-OCT). The following parameters were analyzed: spherical equivalent (SE), uncorrected and corrected distance visual acuity, intraocular pressure (IOP), Shaffer grade of angle opening, lens opacity, goniosyne chiae, choroidal thickness in the macular region, axial length (AL) of the eye, anterior chamber depth (ACD), lens vault (LV), iris curvature (ICurv), iris thickness at 750 µm from scleral spur (IT750), angle opening distance (AOD500, AOD750), iridotrabecular space area (TISA500, TISA750). Along with standard descriptive statistics methods, machine learning methods were used, including Data Driven Soft Independent Modelling of Class Analogies (DD-SIMCA).

RESULTS

RESULTS. Every third eye with PAC had reached control group values after LE (DD-SIMCA specificity 0.67), which was not the case after LPI (DD-SIMCA specificity 1.0) with the probability of getting into the control group estimated as 0.01. After LE, all parameters of the anterior chamber angle did not significantly differ from the norm (p>0.05 for all), while ACD, ICurv even exceeded the norm (p=0.000). After LPI, there was a deepening of the ACD (from 2.34±0.28 mm to 2.36±0.280 mm, p=0.000) and a decrease in LV (from 0.864±0.120 µm to 0.843±0.110 µm, p=0.000), however, the result comparable to control was achieved only in ICurv (p=1.000). After LE in PAC, all parameters, including uncorrected visual acuity, SE, ACD, LV, iris profile, Shaffer grade of angle opening, and AOD500, AOD750, TISA500, TISA750 parameters in the superior and inferior sectors had advantages over those in PACs without treatment (p<0.05). After LPI, an improvement in a number of pa rameters was also achieved compared to LPI: ICurv, Shaffer grade of angle opening, AOD500, AOD750, TISA500, TISA750 in the superior sectors and AOD500 in the inferior sector (p><0.05).

CONCLUSION

CONCLUSION. The effectiveness of LE in PAC is higher than LPI due to the better postoperative anterior chamber topography and lower IOP. Both treatments, especially LE, improve these parameters compared to PACs. Lens extraction is the treatment of choice at the early stages of primary angle closure.

первичное закрытие угла передней камерыподозрение на первичное закрытие углаоптическая когерентная томография с частотно-модулированным источникомоптическая когерентная томография переднего отрезкапериферическая лазерная иридотомияленсэктомияDD-SIMCAметоды машинного обученияprimary angle closureprimary angle closure suspectsswept source optical coherence tomographyanterior segment optical coherence tomographylaser peripheral iridotomylens extractiondata-driven soft independent modelling of class analogiesmachine learningReferencesFoster PJ, Oen FT, Machin D, et al. The prevalence of glaucoma in Chinese residents of Singapore: a cross-sectional population survey of the Tanjong Pagar district. Arch Ophthalmol 2000; 118(8):1105-1111. https://doi.org/10.1001/archopht.118.8.1105Foster PJ, Oen FT, Machin D, et al. The prevalence of glaucoma in Chinese residents of Singapore: a cross-sectional population survey of the Tanjong Pagar district. Arch Ophthalmol 2000; 118(8):1105-1111. https://doi.org/10.1001/archopht.118.8.1105Friedman DS, Foster PJ, Aung T, He M. Angle closure and angle- closure glaucoma: what we are doing now and what we will be doing in the future. Clin Exp Ophthalmol 2012; 40(4):381-387. https://doi.org/10.1111/j.1442-9071.2012.02774.xFriedman DS, Foster PJ, Aung T, He M. Angle closure and angle- closure glaucoma: what we are doing now and what we will be doing in the future. Clin Exp Ophthalmol 2012; 40(4):381-387. https://doi.org/10.1111/j.1442-9071.2012.02774.xZhekov I, Pardhan S, Bourne RR. Optical coherence tomography-measured changes over time in anterior chamber angle and diurnal intraocular pressure after laser iridotomy: IMPACT study. Clin Exp Ophthalmol 2018; 46(8):895-902. https://doi.org/10.1111/ceo.13303Zhekov I, Pardhan S, Bourne RR. Optical coherence tomography-measured changes over time in anterior chamber angle and diurnal intraocular pressure after laser iridotomy: IMPACT study. Clin Exp Ophthalmol 2018; 46(8):895-902. https://doi.org/10.1111/ceo.13303Park HS, Kim JM, Shim SH, et al. Diurnal intraocular pressure changes in eyes affected with acute primary angle closure and fellow eyes after laser peripheral iridotomy. Jpn J Ophthalmol 2015; 59(5):318-324. https://doi.org/10.1007/s10384-015-0399-8Park HS, Kim JM, Shim SH, et al. Diurnal intraocular pressure changes in eyes affected with acute primary angle closure and fellow eyes after laser peripheral iridotomy. Jpn J Ophthalmol 2015; 59(5):318-324. https://doi.org/10.1007/s10384-015-0399-8Guo ZZ, Chang K, Wei X. Intraocular pressure fluctuation and the risk of glaucomatous damage deterioration: a meta-analysis. Int J Ophthalmol 2019; 12(1):123-128. https://doi.org/10.18240/ijo.2019.01.19Guo ZZ, Chang K, Wei X. Intraocular pressure fluctuation and the risk of glaucomatous damage deterioration: a meta-analysis. Int J Ophthalmol 2019; 12(1):123-128. https://doi.org/10.18240/ijo.2019.01.19Sihota R, Rishi K, Srinivasan G, Gupta V, Dada T, Singh K. Functional evaluation of an iridotomy in primary angle closure eyes. Graefe’s Arch Clin Exp Ophthalmol = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologi 2016; 254(6):1141-1149. https://doi.org/10.1007/s00417-016-3298-xSihota R, Rishi K, Srinivasan G, Gupta V, Dada T, Singh K. Functional evaluation of an iridotomy in primary angle closure eyes. Graefe’s Arch Clin Exp Ophthalmol = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologi 2016; 254(6):1141-1149. https://doi.org/10.1007/s00417-016-3298-xLee KS, Sung KR, Kang SY, Cho JW, Kim DY, Kook MS. Residual anterior chamber angle closure in narrow-angle eyes following laser peripheral iridotomy: anterior segment optical coherence tomography quantitative study. Jpn J Ophthalmol 2011; 55(3):213-219. https://doi.org/10.1007/s10384-011-0009-3Lee KS, Sung KR, Kang SY, Cho JW, Kim DY, Kook MS. Residual anterior chamber angle closure in narrow-angle eyes following laser peripheral iridotomy: anterior segment optical coherence tomography quantitative study. Jpn J Ophthalmol 2011; 55(3):213-219. https://doi.org/10.1007/s10384-011-0009-3Nonaka A, Kondo T, Kikuchi M, Yamashiro K, Fujihara M, Iwawaki T, Yamamoto K, Kurimoto Y. Cataract surgery for residual angle closure after peripheral laser iridotomy. Ophthalmology 2005; 112(6): 974-979. https://doi.org/10.1016/j.ophtha.2004.12.042Nonaka A, Kondo T, Kikuchi M, Yamashiro K, Fujihara M, Iwawaki T, Yamamoto K, Kurimoto Y. Cataract surgery for residual angle closure after peripheral laser iridotomy. Ophthalmology 2005; 112(6): 974-979. https://doi.org/10.1016/j.ophtha.2004.12.042Jiang Y, Chang DS, Zhu H, et al. Longitudinal changes of angle configuration in primary angle-closure suspects: the Zhongshan Angle-Closure Prevention Trial. Ophthalmology 2014; 121(9):1699-1705. https://doi.org/10.1016/j.ophtha.2014.03.039Jiang Y, Chang DS, Zhu H, et al. Longitudinal changes of angle configuration in primary angle-closure suspects: the Zhongshan Angle-Closure Prevention Trial. Ophthalmology 2014; 121(9):1699-1705. https://doi.org/10.1016/j.ophtha.2014.03.039Bo J, Changulani T, Cheng ML, Tatham AJ. Outcome Following Laser Peripheral Iridotomy and Predictors of Future Lens Extraction. J Glaucoma 2018; 27(3):275-280. https://doi.org/10.1097/IJG.0000000000000863Bo J, Changulani T, Cheng ML, Tatham AJ. Outcome Following Laser Peripheral Iridotomy and Predictors of Future Lens Extraction. J Glaucoma 2018; 27(3):275-280. https://doi.org/10.1097/IJG.0000000000000863Беликова Е.И., Шарова Г.А. Персонализированный подход к лечению пациентов с латентной стадией закрытоугольной глаукомы. Офтальмология 2020; 17(3s):566-571. https://doi.org/10.18008/1816-5095-2020-3S-566-571Belikova E.I., Sharova G.A. A Personalized Approach to the Treatment of Patients with Latent Stage Angle-Closure Glaucoma. Ophthalmology in Russia 2020; 17(3S):566-571. https://doi.org/10.18008/1816-5095-2020-3S-566-571Song MK, Sung KR, Shin JW, Jo YH, Won HJ. Glaucomatous Progression After Lens Extraction in Primary Angle Closure Disease Spectrum. J Glaucoma 2020; 29(8):711-717. https://doi.org/10.1097/IJG.0000000000001537Song MK, Sung KR, Shin JW, Jo YH, Won HJ. Glaucomatous Progression After Lens Extraction in Primary Angle Closure Disease Spectrum. J Glaucoma 2020; 29(8):711-717. https://doi.org/10.1097/IJG.0000000000001537Siguan-Bell CS, Chansangpetch S, Perez CI, et al. Anterior Segment Parameters of Filipino-Americans Compared to Chinese-Americans and Caucasian Americans Using Anterior Segment Optical Coherence Tomography. Transl Vis Sci Technol 2019; 8(2):11. https://doi.org/10.1167/tvst.8.2.11Siguan-Bell CS, Chansangpetch S, Perez CI, et al. Anterior Segment Parameters of Filipino-Americans Compared to Chinese-Americans and Caucasian Americans Using Anterior Segment Optical Coherence Tomography. Transl Vis Sci Technol 2019; 8(2):11. https://doi.org/10.1167/tvst.8.2.11Azuara-Blanco A., Burr J., Ramsay C., et al. Effectiveness of early lens extraction for the treatment of primary angle-closure glaucoma (EAGLE): a randomised controlled trial. Lancet 2016; 388(10052): 1389-1397. https://doi.org/10.1016/S0140 6736(16)30956-4Azuara-Blanco A., Burr J., Ramsay C., et al. Effectiveness of early lens extraction for the treatment of primary angle-closure glaucoma (EAGLE): a randomised controlled trial. Lancet 2016; 388(10052): 1389-1397. https://doi.org/10.1016/S0140 6736(16)30956-4He M, Jiang Y, Huang S, Chang DS, Munoz B, Aung T, Foster PJ, Friedman DS. Laser peripheral iridotomy for the prevention of angle closure: a single-centre, Randomized controlled trial. Lancet 2019; 393(10181):1609-1618. https://doi.org/10.1016/S0140-6736(18)32607-2He M, Jiang Y, Huang S, Chang DS, Munoz B, Aung T, Foster PJ, Friedman DS. Laser peripheral iridotomy for the prevention of angle closure: a single-centre, Randomized controlled trial. Lancet 2019; 393(10181):1609-1618. https://doi.org/10.1016/S0140-6736(18)32607-2Foster PJ, Buhrmann R, Quigley HA, Johnson GJ. The definition and classification of glaucoma in prevalence surveys. Br J Ophthalmol 2002; 86(2):238-242. https://doi.org10.1136/bjo.86.2.238Foster PJ, Buhrmann R, Quigley HA, Johnson GJ. The definition and classification of glaucoma in prevalence surveys. Br J Ophthalmol 2002; 86(2):238-242. https://doi.org10.1136/bjo.86.2.238Chylack LT Jr, Wolfe JK, Singer DM, et al. The Lens Opacities Classification System III. The Longitudinal Study of Cataract Study Group. Arch Ophthalmol 1993; 111(6):831-836. https://doi.org/10.1001/archopht.1993.01090060119035Chylack LT Jr, Wolfe JK, Singer DM, et al. The Lens Opacities Classification System III. The Longitudinal Study of Cataract Study Group. Arch Ophthalmol 1993; 111(6):831-836. https://doi.org/10.1001/archopht.1993.01090060119035Курышева Н.И., Шарова Г.А. Роль оптической когерентной томографии в диагностике заболеваний закрытого угла передней камеры. Часть 1: Визуализация переднего сегмента глаза. Офтальмология 2021; 18(2):208-215. https://doi.org/10.18008/1816-5095-2021-2-208-215Kurysheva N.I., Sharova G.A. The Role of Optical Coherence Tomography in the Diagnosis of Angle Closed Diseases of the Anterior Chamber. Part 1: Visualization of the Anterior Segment of the Eye. Ophthalmology in Russia 2021; 18(2):208-215. https://doi.org/10.18008/1816-5095-2021-2-208-215Курышева Н.И., Бояринцева М.А., Фомин А.В. Хориоидея при первичной закрытоугольной глаукоме: результаты исследования методом оптической когерентной томографии. Офтальмология 2013; 10(4):26-31. https://doi.org/10.18008/1816-5095-2013-4-26-31Kurysheva N.I., Boyarinceva M.A., Fomin A.V. Choroidal thickness in primary angle-closure glaucoma: the results of Measurement by Means of Optical Coherence Tomography. Ophthalmology in Russia 2013; 10(4):26-31. https://doi.org/10.18008/1816-5095-2013-4-26-31Rodionova O. Ye., Kurysheva N.I., Sharova G.A., Pomerantsev A.L. Expanding the DD-SIMCA concept: A case study of precision medicine. Analytica Chimica Acta 2023; 1250, 340958, ISSN 0003-2670. https://doi.org/10.1016/j.aca.2023.340958Rodionova O. Ye., Kurysheva N.I., Sharova G.A., Pomerantsev A.L. Expanding the DD-SIMCA concept: A case study of precision medicine. Analytica Chimica Acta 2023; 1250, 340958, ISSN 0003-2670. https://doi.org/10.1016/j.aca.2023.340958Курышева Н.И., Померанцев А.Л., Родионова О.Е., Шарова Г.А. Методы машинного обучения в сравнительной оценке различных подходов к хирургическому лечению первичного закрытия угла передней камеры глаза. Офтальмология 2022;19(3):549-556. https://doi.org/10.18008/1816-5095-2022-3-549-556Kurysheva N.I., Pomerantsev A.L., Rodionova O.Y., Sharova G.A. Machine Learning Methods in the Comparative Evaluation of Various Approaches to the Surgical Treatment of Primary Angle Closure. Ophthalmology in Russia 2022; 19(3):549-556. https://doi.org/10.18008/1816-5095-2022-3-549-556Pomerantsev A.L. Acceptance areas for multivariate classification derived by projection methods. J Chemometrics 2008; 22:601-609. https://doi.org/10.1002/cem.1147Pomerantsev A.L. Acceptance areas for multivariate classification derived by projection methods. J Chemometrics 2008; 22:601-609. https://doi.org/10.1002/cem.1147Pomerantsev A.L., Rodionova O.Ye. Concept and role of extreme objects in PCA/SIMCA. J Chemometrics 2014; 28:429-438. https://doi.org/10.1002/cem.2506Pomerantsev A.L., Rodionova O.Ye. Concept and role of extreme objects in PCA/SIMCA. J Chemometrics 2014; 28:429-438. https://doi.org/10.1002/cem.2506Pomerantsev A.L., Rodionova O.Ye. On the type II error in SIMCA method. J Chemometrics 2014; 28:518-522. https://doi.org/10.1002/cem.2610Pomerantsev A.L., Rodionova O.Ye. On the type II error in SIMCA method. J Chemometrics 2014; 28:518-522. https://doi.org/10.1002/cem.2610Dada T, Rathi A, Angmo D, et al. Clinical outcomes of clear lens extraction in eyes with primary angle closure. J Cataract Refract Surg 2015; 41(7):1470-1477. https://doi.org/10.1016/j.jcrs.2014.10.029Dada T, Rathi A, Angmo D, et al. Clinical outcomes of clear lens extraction in eyes with primary angle closure. J Cataract Refract Surg 2015; 41(7):1470-1477. https://doi.org/10.1016/j.jcrs.2014.10.029Zhang Y, Thomas R, Zhang Q, Li SZ, Wang NL. Progression of Primary Angle Closure Suspect to Primary Angle Closure and Associated Risk Factors: The Handan Eye Study. Invest Ophthalmol Vis Sci 2021; 62(7):2. https://doi.org/10.1167/iovs.62.7.2Zhang Y, Thomas R, Zhang Q, Li SZ, Wang NL. Progression of Primary Angle Closure Suspect to Primary Angle Closure and Associated Risk Factors: The Handan Eye Study. Invest Ophthalmol Vis Sci 2021; 62(7):2. https://doi.org/10.1167/iovs.62.7.2Moghimi S, Chen R, Johari M, Bijani F, Mohammadi M, Khodabandeh A, He M, Lin SC. Changes in Anterior Segment Morphology After Laser Peripheral Iridotomy in Acute Primary Angle Closure. Am J Ophthalmol 2016; 166:133-140. https://doi.org/10.1016/j.ajo.2016.03.032Moghimi S, Chen R, Johari M, Bijani F, Mohammadi M, Khodabandeh A, He M, Lin SC. Changes in Anterior Segment Morphology After Laser Peripheral Iridotomy in Acute Primary Angle Closure. Am J Ophthalmol 2016; 166:133-140. https://doi.org/10.1016/j.ajo.2016.03.032Ang BC, Nongpiur ME, Aung T, Mizoguchi T, Ozaki M. Changes in Japanese eyes after laser peripheral iridotomy: an anterior segment optical coherence tomography study. Clin Exp Ophthalmol 2016; 44(3): 159-165. https://doi.org/10.1111/ceo.12673Ang BC, Nongpiur ME, Aung T, Mizoguchi T, Ozaki M. Changes in Japanese eyes after laser peripheral iridotomy: an anterior segment optical coherence tomography study. Clin Exp Ophthalmol 2016; 44(3): 159-165. https://doi.org/10.1111/ceo.12673Lee RY, Kasuga T, Cui QN, et al. Association between baseline iris thickness and prophylactic laser peripheral iridotomy outcomes in primary angle-closure suspects. Ophthalmology 2014; 121(6):1194-1202. https://doi.org/10.1016/j.ophtha.2013.12.027Lee RY, Kasuga T, Cui QN, et al. Association between baseline iris thickness and prophylactic laser peripheral iridotomy outcomes in primary angle-closure suspects. Ophthalmology 2014; 121(6):1194-1202. https://doi.org/10.1016/j.ophtha.2013.12.027Wang N, Ouyang J, Zhou W, Lai M, Ye T, Zeng M, Chen J. [Multiple patterns of angle closure mechanisms in primary angle closure glaucoma in Chinese]. Zhonghua Yan Ke Za Zhi 2000; 36(1):46-6. Chinese.Wang N, Ouyang J, Zhou W, Lai M, Ye T, Zeng M, Chen J. [Multiple patterns of angle closure mechanisms in primary angle closure glaucoma in Chinese]. Zhonghua Yan Ke Za Zhi 2000; 36(1):46-6. Chinese.Mak H, Xu G, Leung CK. Imaging the iris with swept-source optical coherence tomography: relationship between iris volume and primary angle closure. Ophthalmology 2013; 120(12):2517-2524. https://doi.org/10.1016/j.ophtha.2013.05.009Mak H, Xu G, Leung CK. Imaging the iris with swept-source optical coherence tomography: relationship between iris volume and primary angle closure. Ophthalmology 2013; 120(12):2517-2524. https://doi.org/10.1016/j.ophtha.2013.05.009Yan C, Han Y, Yu Y, et al. Effects of lens extraction versus laser peripheral iridotomy on anterior segment morphology in primary angle closure suspect. Graefes Arch Clin Exp Ophthalmol 2019; 257(7):1473-1480. https://doi.org/10.1007/s00417-019-04353-8Yan C, Han Y, Yu Y, et al. Effects of lens extraction versus laser peripheral iridotomy on anterior segment morphology in primary angle closure suspect. Graefes Arch Clin Exp Ophthalmol 2019; 257(7):1473-1480. https://doi.org/10.1007/s00417-019-04353-8Курышева Н.И., Шарова Г.А., Беликова Е.И. Исследование роли хориоидеи и хрусталика в развитии первичного закрытия угла передней камеры. Национальный журнал Глаукома. 2022; 21(1):3-13. https://doi.org/10.53432/2078-4104-2022-21-1-3-13Kurysheva N.I., Sharova G.A., Belikova E.I. Studying the role of the choroid and lens in the development of primary anterior chamber angle closure. National Journal glaucoma 2022; 21(1):3-13. https://doi.org/10.53432/2078-4104-2022-21-1-3-13Курышева Н.И., Шарова Г.А. Сравнительное исследование ретинальной микроциркуляции при заболевании первичного закрытого угла и начальной первичной открытоугольной глаукоме. Вестник офтальмологии 2022; 138(1):44-51. https://doi.org/10.17116/oftalma20221380114451.Kurysheva NI, Sharova GA. Comparative study of retinal microcirculation in primary angle closure disease and early primary open-angle glaucoma. Vestnik Oftalmologii 2022; 138(1):44-51. (In Russ.). https://doi.org/10.17116/oftalma20221380114451.Ghadamzadeh M, Karimi F, Ghasemi Moghaddam S, Daneshvar R. Anterior Chamber Angle Changes in Primary Angle-closure Glaucoma Following Phacoemulsification Versus Phacotrabeculectomy: A Prospective Randomized Clinical Trial. J Glaucoma 2022; 31(3):147-155. https://10.1097/IJG.0000000000001977Ghadamzadeh M, Karimi F, Ghasemi Moghaddam S, Daneshvar R. Anterior Chamber Angle Changes in Primary Angle-closure Glaucoma Following Phacoemulsification Versus Phacotrabeculectomy: A Prospective Randomized Clinical Trial. J Glaucoma 2022; 31(3):147-155. https://10.1097/IJG.0000000000001977Yun-Hsuan Lin, Cheng-Hsiu Wu, Shih-Ming Huang, Chen Hsieh, Henry Shen-Lih Chen, Wan-Chen Ku, Ming-Hui Sun, Wei-Wen Su. Early versus Delayed Phacoemulsification and Intraocular Lens Implantation for Acute Primary Angle-Closure. J Ophthalmol 2020; 2020:8319570. https://10.1155/2020/8319570Yun-Hsuan Lin, Cheng-Hsiu Wu, Shih-Ming Huang, Chen Hsieh, Henry Shen-Lih Chen, Wan-Chen Ku, Ming-Hui Sun, Wei-Wen Su. Early versus Delayed Phacoemulsification and Intraocular Lens Implantation for Acute Primary Angle-Closure. J Ophthalmol 2020; 2020:8319570. https://10.1155/2020/8319570Aung T, Ang LP, Chan SP, Chew PT. Acute primary angle-closure: long-term intraocular pressure outcome in Asian eyes. Am J Ophthalmol 2001; 131(1):7-12. https://10.1016/s0002-9394(00)00621-8Aung T, Ang LP, Chan SP, Chew PT. Acute primary angle-closure: long-term intraocular pressure outcome in Asian eyes. Am J Ophthalmol 2001; 131(1):7-12. https://10.1016/s0002-9394(00)00621-8Zuo C, Long B, Guo X, Chen L, Liu X. Effect of Phacoemulsification on Anterior Chamber Angle in Eyes with Medically Uncontrolled Filtered Primary Angle-Closure Glaucoma. J Ophthalmol 2020; 2020:8720450. https://10.1155/2020/8720450Zuo C, Long B, Guo X, Chen L, Liu X. Effect of Phacoemulsification on Anterior Chamber Angle in Eyes with Medically Uncontrolled Filtered Primary Angle-Closure Glaucoma. J Ophthalmol 2020; 2020:8720450. https://10.1155/2020/8720450Курышева Н.И., Шарова Г.А. Эффективность лазерной иридотомии при подозрении на первичное закрытие угла и при первичной закрытоугольной глаукоме. The EYE ГЛАЗ 2022; 24(1):20-33. https://doi.org/10.33791/2222-4408-2022-1-20-33Kurysheva N.I., Sharova G.A. Efficacy of laser iridotomy in primary angle closure suspects and primary angle closure glaucoma. The EYE GLAZ 2022; 24(1):20-33. https://doi.org/10.33791/2222-4408-2022-1-20-33

The authors declare that there are no conflicts of interest present.