glaucomaНациональный журнал ГлаукомаNational Journal glaucoma2078-41042311-6862Federal State Budgetary Institution of Science “Krasnov Research Institute of Eye Diseases”10.53432/2078-4104-2024-23-2-95-106glaucoma-527Research ArticleОБЗОРЫ ЛИТЕРАТУРЫLITERATURE REVIEWSДиагностические возможности современных приборов в оценке морфометрических изменений при глаукомеDiagnostic possibilities of modern devices for evaluation of morphometric changes in glaucomahttps://orcid.org/0009-0007-5416-2063СеменовЕ. Д.SemenovE. D.

Семенов Евгений Дмитриевич, ординатор

119021, Москва, ул. Россолимо, 11А

clinical resident

11A Rossolimo St., Moscow, 119021

208_semenoved@mail.ruhttps://orcid.org/0000-0001-7735-9650ВитковА. А.VitkovA. A.

младший научный сотрудник отдела глаукомы

119021, Москва, ул. Россолимо, 11А

Junior Researcher at the Glaucoma Department

11A Rossolimo St., Moscow, 119021

https://orcid.org/0000-0003-3885-9649КозловаИ. В.KozlovaI. V.

к.м.н., ведущий научный сотрудник отдела глаукомы

119021, Москва, ул. Россолимо, 11А

Cand. Sci. (Med.), Leading Researcher at the Glaucoma Department

11A Rossolimo St., Moscow, 119021

https://orcid.org/0000-0003-2893-0173АсиновсковаИ. И.AsinovskovaI. I.

ординатор

119021, Москва, ул. Россолимо, 11А

clinical resident

11A Rossolimo St., Moscow, 119021

ФГБНУ «НИИГБ им. М.М. Краснова»РоссияKrasnov Research Institute of Eye DiseasesRussian Federation20242606202423295106Copyright © Семенов Е.Д., Витков А.А., Козлова И.В., Асиновскова И.И., 20242024Семенов Е.Д., Витков А.А., Козлова И.В., Асиновскова И.И.Semenov E.D., Vitkov A.A., Kozlova I.V., Asinovskova I.I.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.glaucomajournal.ru/jour/article/view/527

Первичная открытоугольная глаукома (ПОУГ) — хроническая оптическая нейропатия, характеризующаяся потерей ганглиозных клеток с развитием специфических изменений диска зрительного нерва (ДЗН). Выявление структурных глаукомных изменений необходимо как для верификации диагноза, так и для оценки эффективности гипотензивной терапии.

В настоящее время в клинической практике имеется ряд приборов, позволяющих провести объективный морфометрический анализ ДЗН: конфокальная лазерная сканирующая офтальмоскопия (гейдельберская ретинотомография, HRT), сканирующая лазерная поляриметрия (англ. scanning laser polarimetry, SLP, GDx) оптическая когерентная томография и оптическая когерентная томография с ангиографией. Вышеупомянутые приборы обладают разными принципами исследования и отличаются диагностическими возможностями в обнаружении структурных изменений и выявлении их динамики. В настоящее время методом выбора для диагностики и мониторинга структурных изменений при глаукоме является оптическая когерентная томография.

Primary open-angle glaucoma (POAG) is a chronic optic neuropathy characterized by the loss of ganglion cells and the development of specific changes in the optic nerve head (ONH). Identification of structural glaucomatous changes is necessary both to verify the diagnosis and to determine the effectiveness of antihypertensive therapy.

Currently there are several devices used in clinical practice that allow for an objective morphometric analysis: confocal laser scanning ophthalmoscopy (Heidelberg retinotomography, HRT), scanning laser polarimetry (SLP, GDx), optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA).

These devices have different examination principles and differ in their diagnostic possibilities for detecting structural changes and identifying the trends in glaucoma patients.

глаукомаконфокальная сканирующая лазерная офтальмоскопиясканирующая лазерная поляриметрияоптическая когерентная томографияоптическая когерентная томография ангиографияglaucomaconfocal scanning laser ophthalmoscopyscanning laser polarimetryoptical coherence tomographyoptical coherence tomography angiographyReferencesQuigley HA, Broman AT. The number of people with glaucoma world-wide in 2010 and 2020. Br J Ophthalmol 2006; 90(3):262-267. https://doi.org/10.1136/bjo.2005.081224.Quigley HA, Broman AT. The number of people with glaucoma world-wide in 2010 and 2020. Br J Ophthalmol 2006; 90(3):262-267. https://doi.org/10.1136/bjo.2005.081224.Tham YC, Li X, Wong TY, Quigley HA, Aung T, Cheng CY. Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. Ophthalmology 2014; 121(11):2081-2090. https://doi.org/10.1016/j.ophtha.2014.05.013.Tham YC, Li X, Wong TY, Quigley HA, Aung T, Cheng CY. Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. Ophthalmology 2014; 121(11):2081-2090. https://doi.org/10.1016/j.ophtha.2014.05.013.Основные показатели первичной инвалидности взрослого населения Российской Федерации за 2021 год. ФГБУ «Центральный научно-исследовательский институт организации и информатизации здравоохранения»: Министерство здравоохранения Российской Федерации; 2022. 100 с.The main indicators of primary disability of the adult population of the Russian Federation for 2021. Federal State Budgetary Institution "Central Research Institute of Health Organization and Informatization": Ministry of Health of the Russian Federation; 2022. 100 p.Национальное руководство по глаукоме для практикующих врачей. Изд. 4-е, испр. и доп. Под ред. Егорова Е.А., Еричева В.П. М: ГЭОТАР-Медиа 2019; 384.National Guidelines for Glaucoma Practitioners. Ed. 4th, rev. and additional. Egorov E.A., Erichev V.P., eds. Moscow, GEOTAR-Media Publ., 2019. 384 p.European Glaucoma Society Terminology and Guidelines for Glaucoma, 5th Edition. Br J Ophthalmol 2021; 105(Suppl 1):1-169. https://doi.org/10.1136/bjophthalmol-2021-egsguidelines.European Glaucoma Society Terminology and Guidelines for Glaucoma, 5th Edition. Br J Ophthalmol 2021; 105(Suppl 1):1-169. https://doi.org/10.1136/bjophthalmol-2021-egsguidelines.Еричев В.П., Антонов А.А., Витков А.А., Григорян Л.А. Статическая периметрия в диагностике глаукомы. Часть 1. Базовые принципы. Вестник офтальмологии 2021; 137(5-2):281-288. https://doi.org/10.17116/oftalma2021137052281Erichev VP, Antonov AA, Vitkov AA, Grigoryan LA. Static automated perimetry in the diagnosis of glaucoma. Part 1: Basic principles. Vestnik Oftalmologii 2021; 137(52):281-288. https://doi.org/10.17116/oftalma2021137052281Еричев В.П., Антонов А.А., Витков А.А., Григорян Л.А. Статическая периметрия в диагностике глаукомы. Часть 2. Протокол исследования, классификации глаукомы, периметрические дефекты через призму структурно-функциональной корреляции. Вестник офтальмологии 2021; 137(5-2):289299. https://doi.org/10.17116/oftalma2021137052289Erichev VP, Antonov AA, Vitkov AA, Grigoryan LA. Static automated perimetry in the diagnosis of glaucoma. Part 2: Research protocol, glaucoma classifications, perimetric defects through the prism of structuralfunctional correlation. Vestnik Oftalmologii 2021; 137(52): 289-299. https://doi.org/10.17116/oftalma2021137052289.Антонов А.А., Козлова И.В., Витков А.А. Максимальная медикаментозная терапия глаукомы — что есть в нашем арсенале? Национальный журнал глаукома 2020; 19(2):51-58. https://doi.org/10.25700/NJG.2020.02.06Antonov A.A., Kozlova I.V., Vitkov A.A. Maximum medical therapy for glaucoma — what is in our arsenal? Natsional’nyi zhurnal glaukoma 2020; 19(2):51-58. https://doi.org/10.25700/NJG.2020.02.06Еричев В.П., Онищенко А.Л., Куроедов А.В., Петров С.Ю., Брежнев А.Ю., Антонов А.А., Витков А.А., Мураховска Ю.К. Офтальмологические факторы риска развития первичной открытоугольно глаукомы. Российский медицинский журнал. РМЖ Клиническая офтальмология 2019; 2:81-86. https://doi.org/10.323642311772920191928186Erichev V.P., Onishchenko A.L., Kuroedov A.V., Petrov S.Yu., Brezhnev A.Yu., Antonov A.A., Vitkov A.A., Murakhovskaya Yu.K. Ophthalmic risk factors for the development of primary openangle glaucoma. RMJ Clinical ophthtalmology 2019; 2:81-86. https://doi.org/10.323642311772920191928186Еричев В.П., Петров С.Ю., Козлова И.В., Макарова А.С., Рещикова В.С. Современные методы функциональной диагностики и мониторинга глаукомы. Часть 3. Роль морфофункциональных взаимоотношений в раннем выявлении и мониторинге глаукомы. Национальный журнал глаукома 2016; 15(2):96-101.Erichev V.P., Petrov S.Yu., Kozlova I.V., Makarova A.S., Reshchikova V.S. Modern methods of functional diagnostics and monitoring of glaucoma. Part 3. The role of the morphological and functional relationships in the early detection and monitoring of glaucoma. Natsional’nyi zhurnal glaukoma 2016; 15(2):96-101.Kotowski J, Wollstein G, Ishikawa H, Schuman JS. Imaging of the optic nerve and retinal nerve fiber layer: an essential part of glaucoma diagnosis and monitoring. Surv Ophthalmol 2014; 59(4):458-467. https://doi.org/10.1016/j.survophthal.2013.04.007.Kotowski J, Wollstein G, Ishikawa H, Schuman JS. Imaging of the optic nerve and retinal nerve fiber layer: an essential part of glaucoma diagnosis and monitoring. Surv Ophthalmol 2014; 59(4):458-467. https://doi.org/10.1016/j.survophthal.2013.04.007.Агаева Ф.А., Эфендиева М.Э. Гейдельбергская ретинальная томография. Офтальмология 2013; 3(13):93-96Agaeva F.A., Efendieva M.E. Heidelberg retinal tomography. Oftal’mologiya, 2013; 3(13):93-96.Vessani RM, Moritz R, Batis L, Zagui RB, Bernardoni S, Susanna R. Comparison of quantitative imaging devices and subjective optic nerve head assessment by general ophthalmologists to differentiate normal from glaucomatous eyes. J Glaucoma 2009; 18(3):253-261. https://doi.org/10.1097/IJG.0b013e31818153da.Vessani RM, Moritz R, Batis L, Zagui RB, Bernardoni S, Susanna R. Comparison of quantitative imaging devices and subjective optic nerve head assessment by general ophthalmologists to differentiate normal from glaucomatous eyes. J Glaucoma 2009; 18(3):253-261. https://doi.org/10.1097/IJG.0b013e31818153da.Harasymowycz PJ, Papamatheakis DG, Fansi AK, Gresset J, Lesk MR. Validity of screening for glaucomatous optic nerve damage using confocal scanning laser ophthalmoscopy (Heidelberg Retina Tomagraph II) in high-risk populations: a pilot study. Ophthalmology 2005; 112(12):2164-2171. https://doi.org/10.1016/j.ophtha.2005.09.009.Harasymowycz PJ, Papamatheakis DG, Fansi AK, Gresset J, Lesk MR. Validity of screening for glaucomatous optic nerve damage using confocal scanning laser ophthalmoscopy (Heidelberg Retina Tomograph II) in high-risk populations: a pilot study. Ophthalmology 2005; 112(12):2164-2171. https://doi.org/10.1016/j.ophtha.2005.09.009.Betz P. Photographie stéréoscopique et photogrammétrie de l'excavation physiologique de la papille. 1981.Betz P. Photographie stéréoscopique et photogrammétrie de l'excavation physiologique de la papille. 1981.Iester M, Mikelberg FS, Drance SM. The effect of optic disc size on diagnostic precision with the Heidelberg retina tomograph. Ophthalmology 1997; 104(3):545-548. https://doi.org/10.1016/s0161-6420(97)30277-2.Iester M, Mikelberg FS, Drance SM. The effect of optic disc size on diagnostic precision with the Heidelberg retina tomograph. Ophthalmology 1997; 104(3):545-548. https://doi.org/10.1016/s0161-6420(97)30277-2.Koch EC, Plange N, Fuest M, Schimitzek H, Kuerten D. [Diagnostic Precision of the Confocal Scanning Laser Ophthalmoscopy in the Large Optic Disc with Physiological Excavation — a Long-Term Study]. Klin Monbl Augenheilkd 2019; 236(1):88-95. https://doi.org/10.1055/s-0043-111798.Koch EC, Plange N, Fuest M, Schimitzek H, Kuerten D. [Diagnostic Precision of the Confocal Scanning Laser Ophthalmoscopy in the Large Optic Disc with Physiological Excavation — a Long-Term Study]. Klin Monbl Augenheilkd 2019; 236(1):88-95. https://doi.org/10.1055/s-0043-111798.Healey PR, Lee AJ, Aung T, Wong TY, Mitchell P. Diagnostic accuracy of the Heidelberg Retina Tomograph for glaucoma a population-based assessment. Ophthalmology 2010; 117(9):1667-1673. https://doi.org/10.1016/j.ophtha.2010.07.001.Healey PR, Lee AJ, Aung T, Wong TY, Mitchell P. Diagnostic accuracy of the Heidelberg Retina Tomograph for glaucoma a population-based assessment. Ophthalmology 2010; 117(9):1667-1673. https://doi.org/10.1016/j.ophtha.2010.07.001.Zheng Y, Wong TY, Lamoureux E, Mitchell P, Loon SC, Saw SM, Aung T. Diagnostic ability of Heidelberg Retina Tomography in detecting glaucoma in a population setting: the Singapore Malay Eye Study. Ophthalmology 2010; 117(2):290-297. https://doi.org/10.1016/j.ophtha.2009.07.018.Zheng Y, Wong TY, Lamoureux E, Mitchell P, Loon SC, Saw SM, Aung T. Diagnostic ability of Heidelberg Retina Tomography in detecting glaucoma in a population setting: the Singapore Malay Eye Study. Ophthalmology 2010; 117(2):290-297. https://doi.org/10.1016/j.ophtha.2009.07.018.Wollstein G, Garway-Heath DF, Fontana L, Hitchings RA. Identifying early glaucomatous changes. Comparison between expert clinical assessment of optic disc photographs and confocal scanning ophthalmoscopy. Ophthalmology 2000; 107(12):2272-2277. https://doi.org/10.1016/s0161-6420(00)00363-8.Wollstein G, Garway-Heath DF, Fontana L, Hitchings RA. Identifying early glaucomatous changes. Comparison between expert clinical assessment of optic disc photographs and confocal scanning ophthalmoscopy. Ophthalmology 2000; 107(12):2272-2277. https://doi.org/10.1016/s0161-6420(00)00363-8.Swindale NV, Stjepanovic G, Chin A, Mikelberg FS. Automated analysis of normal and glaucomatous optic nerve head topography images. Invest Ophthalmol Vis Sci 2000; 41(7):1730-1742.Swindale NV, Stjepanovic G, Chin A, Mikelberg FS. Automated analysis of normal and glaucomatous optic nerve head topography images. Invest Ophthalmol Vis Sci 2000; 41(7):1730-1742.Куроедов А.В., Городничий В.В. Компьютерная ретинотомография (HRT): диагностика, динамика, достоверность. М: 2007; 236.Kuroyedov A.V., Gorodnichiy V.V. Computed retinotomography (HRT): diagnostics, dynamics, reliability. Moscow, 2007. 236 p.Danias J, Serle J. Can Visual Field Progression be Predicted by Confocal Scanning Laser Ophthalmoscopic Imaging of the Optic Nerve Head in Glaucoma? (An American Ophthalmological Society Thesis). Trans Am Ophthalmol Soc 2015; 113:T4.Danias J, Serle J. Can Visual Field Progression be Predicted by Confocal Scanning Laser Ophthalmoscopic Imaging of the Optic Nerve Head in Glaucoma? (An American Ophthalmological Society Thesis). Trans Am Ophthalmol Soc 2015; 113:T4.Saarela V, Falck A, Airaksinen PJ, Tuulonen A. The sensitivity and specificity of Heidelberg Retina Tomograph parameters to glaucomatous progression in disc photographs. Br J Ophthalmol 2010; 94(1): 68-73. https://doi.org/10.1136/bjo.2009.159251.Saarela V, Falck A, Airaksinen PJ, Tuulonen A. The sensitivity and specificity of Heidelberg Retina Tomograph parameters to glaucomatous progression in disc photographs. Br J Ophthalmol 2010; 94(1): 68-73. https://doi.org/10.1136/bjo.2009.159251.Bowd C, Balasubramanian M, Weinreb RN, Vizzeri G, Alencar LM, O'Leary N, Sample PA, Zangwill LM. Performance of confocal scanning laser tomograph Topographic Change Analysis (TCA) for assessing glaucomatous progression. Invest Ophthalmol Vis Sci 2009; 50(2): 691-701. https://doi.org/10.1167/iovs.08-2136.Bowd C, Balasubramanian M, Weinreb RN, Vizzeri G, Alencar LM, O'Leary N, Sample PA, Zangwill LM. Performance of confocal scanning laser tomograph Topographic Change Analysis (TCA) for assessing glaucomatous progression. Invest Ophthalmol Vis Sci 2009; 50(2): 691-701. https://doi.org/10.1167/iovs.08-2136.Chauhan BC, Hutchison DM, Artes PH, Caprioli J, Jonas JB, LeBlanc RP, Nicolela MT. Optic disc progression in glaucoma: comparison of confocal scanning laser tomography to optic disc photographs in a prospective study. Invest Ophthalmol Vis Sci 2009; 50(4):1682-1691. https://doi.org/10.1167/iovs.08-2457.Chauhan BC, Hutchison DM, Artes PH, Caprioli J, Jonas JB, LeBlanc RP, Nicolela MT. Optic disc progression in glaucoma: comparison of confocal scanning laser tomography to optic disc photographs in a prospective study. Invest Ophthalmol Vis Sci 2009; 50(4):1682-1691. https://doi.org/10.1167/iovs.08-2457.Quigley HA, Katz J, Derick RJ, Gilbert D, Sommer A. An evaluation of optic disc and nerve fiber layer examinations in monitoring progression of early glaucoma damage. Ophthalmology 1992; 99(1):19-28. https://doi.org/10.1016/s0161-6420(92)32018-4.Quigley HA, Katz J, Derick RJ, Gilbert D, Sommer A. An evaluation of optic disc and nerve fiber layer examinations in monitoring progression of early glaucoma damage. Ophthalmology 1992; 99(1):19-28. https://doi.org/10.1016/s0161-6420(92)32018-4.Weinreb RN, Bowd C, Zangwill LM. Glaucoma detection using scanning laser polarimetry with variable corneal polarization compensation. Arch Ophthalmol 2003; 121(2):218-224. https://doi.org/10.1001/archopht.121.2.218.Weinreb RN, Bowd C, Zangwill LM. Glaucoma detection using scanning laser polarimetry with variable corneal polarization compensation. Arch Ophthalmol 2003; 121(2):218-224. https://doi.org/10.1001/archopht.121.2.218.Reus NJ, Lemij HG. Scanning laser polarimetry of the retinal nerve fiber layer in perimetrically unaffected eyes of glaucoma patients. Ophthalmology 2004;111(12):2199-2203. https://doi.org/10.1016/j.ophtha.2004.06.018.Reus NJ, Lemij HG. Scanning laser polarimetry of the retinal nerve fiber layer in perimetrically unaffected eyes of glaucoma patients. Ophthalmology 2004;111(12):2199-2203. https://doi.org/10.1016/j.ophtha.2004.06.018.Zheng W, Baohua C, Qun C, Zhi Q, Hong D. Retinal nerve fiber layer images captured by GDx-VCC in early diagnosis of glaucoma. Ophthalmologica 2008; 222(1):17-20. https://doi.org/10.1159/000109273.Zheng W, Baohua C, Qun C, Zhi Q, Hong D. Retinal nerve fiber layer images captured by GDx-VCC in early diagnosis of glaucoma. Ophthalmologica 2008; 222(1):17-20. https://doi.org/10.1159/000109273.Dimopoulos AT, Katsanos A, Mikropoulos DG, Giannopoulos T, Empeslidis T, Teus MA, Hollo G, Konstas AG. Scanning laser polarimetry in eyes with exfoliation syndrome. Eur J Ophthalmol 2013; 23(5): 743-750. https://doi.org/10.5301/ejo.5000247.Dimopoulos AT, Katsanos A, Mikropoulos DG, Giannopoulos T, Empeslidis T, Teus MA, Hollo G, Konstas AG. Scanning laser polarimetry in eyes with exfoliation syndrome. Eur J Ophthalmol 2013; 23(5): 743-750. https://doi.org/10.5301/ejo.5000247.Ara M, Ferreras A, Pajarin AB, Calvo P, Figus M, Frezzotti P. Repeatability and Reproducibility of Retinal Nerve Fiber Layer Parameters Measured by Scanning Laser Polarimetry with Enhanced Corneal Compensation in Normal and Glaucomatous Eyes. Biomed Res Int 2015; 2015:729392. https://doi.org/10.1155/2015/729392.Ara M, Ferreras A, Pajarin AB, Calvo P, Figus M, Frezzotti P. Repeatability and Reproducibility of Retinal Nerve Fiber Layer Parameters Measured by Scanning Laser Polarimetry with Enhanced Corneal Compensation in Normal and Glaucomatous Eyes. Biomed Res Int 2015; 2015:729392. https://doi.org/10.1155/2015/729392.Wang Z, Liu XW, Li XY, Zhang WJ, Dai H. [Detection of the changes of retinal nerve fiber layer thickness by GDx-VCC laser scanning polarimetry in primary open angle glaucoma patients]. Zhonghua Yan Ke Za Zhi 2012; 48(6):497-501.Wang Z, Liu XW, Li XY, Zhang WJ, Dai H. [Detection of the changes of retinal nerve fiber layer thickness by GDx-VCC laser scanning polarimetry in primary open angle glaucoma patients]. Zhonghua Yan Ke Za Zhi 2012; 48(6):497-501.Wang G, Qiu KL, Lu XH, Sun LX, Liao XJ, Chen HL, Zhang MZ. The effect of myopia on retinal nerve fibre layer measurement: a comparative study of spectral-domain optical coherence tomography and scanning laser polarimetry. Br J Ophthalmol 2011; 95(2):255-260. https://doi.org/10.1136/bjo.2009.176768.Wang G, Qiu KL, Lu XH, Sun LX, Liao XJ, Chen HL, Zhang MZ. The effect of myopia on retinal nerve fibre layer measurement: a comparative study of spectral-domain optical coherence tomography and scanning laser polarimetry. Br J Ophthalmol 2011; 95(2):255-260. https://doi.org/10.1136/bjo.2009.176768.Dada T, Aggarwal A, Bali SJ, Sharma A, Shah BM, Angmo D, Panda A. Evaluation of retinal nerve fiber layer thickness parameters in myopic population using scanning laser polarimetry (GDxVCC). Nepal J Ophthalmol 2013; 5(1):3-8. https://doi.org/10.3126/nepjoph.v5i1.7814.Dada T, Aggarwal A, Bali SJ, Sharma A, Shah BM, Angmo D, Panda A. Evaluation of retinal nerve fiber layer thickness parameters in myopic population using scanning laser polarimetry (GDxVCC). Nepal J Ophthalmol 2013; 5(1):3-8. https://doi.org/10.3126/nepjoph.v5i1.7814.Yu S, Tanabe T, Hangai M, Morishita S, Kurimoto Y, Yoshimura N. Scanning laser polarimetry with variable corneal compensation and optical coherence tomography in tilted disk. Am J Ophthalmol 2006; 142(3):475-482. https://doi.org/10.1016/j.ajo.2006.04.053.Yu S, Tanabe T, Hangai M, Morishita S, Kurimoto Y, Yoshimura N. Scanning laser polarimetry with variable corneal compensation and optical coherence tomography in tilted disk. Am J Ophthalmol 2006; 142(3):475-482. https://doi.org/10.1016/j.ajo.2006.04.053.Bozkurt B, Irkec M, Tatlipinar S, Erdener U, Orhan M, Gedik S, Karaagaoglu E. Retinal nerve fiber layer analysis and interpretation of GDx parameters in patients with tilted disc syndrome. Int Ophthalmol 2001; 24(1):27-31. https://doi.org/10.1023/a:1014490414688.Bozkurt B, Irkec M, Tatlipinar S, Erdener U, Orhan M, Gedik S, Karaagaoglu E. Retinal nerve fiber layer analysis and interpretation of GDx parameters in patients with tilted disc syndrome. Int Ophthalmol 2001; 24(1):27-31. https://doi.org/10.1023/a:1014490414688.Huang D, Swanson EA, Lin CP, Schuman JS, Stinson WG, Chang W, Hee MR, Flotte T, Gregory K, Puliafito CA, et al. Optical coherence tomography. Science 1991; 254(5035):1178-1181. https://doi.org/10.1126/science.1957169.Huang D, Swanson EA, Lin CP, Schuman JS, Stinson WG, Chang W, Hee MR, Flotte T, Gregory K, Puliafito CA, et al. Optical coherence tomography. Science 1991; 254(5035):1178-1181. https://doi.org/10.1126/science.1957169.Schuman JS, Hee MR, Arya AV, Pedut-Kloizman T, Puliafito CA, Fujimoto JG, Swanson EA. Optical coherence tomography: a new tool for glaucoma diagnosis. Curr Opin Ophthalmol 1995; 6(2):89-95. https://doi.org/10.1097/00055735-199504000-00014.Schuman JS, Hee MR, Arya AV, Pedut-Kloizman T, Puliafito CA, Fujimoto JG, Swanson EA. Optical coherence tomography: a new tool for glaucoma diagnosis. Curr Opin Ophthalmol 1995; 6(2):89-95. https://doi.org/10.1097/00055735-199504000-00014.Schuman JS, Hee MR, Puliafito CA, Wong C, Pedut-Kloizman T, Lin CP, Hertzmark E, Izatt JA, Swanson EA, Fujimoto JG. Quantification of nerve fiber layer thickness in normal and glaucomatous eyes using optical coherence tomography. Arch Ophthalmol 1995; 113(5):586-596. https://doi.org/10.1001/archopht.1995.01100050054031.Schuman JS, Hee MR, Puliafito CA, Wong C, Pedut-Kloizman T, Lin CP, Hertzmark E, Izatt JA, Swanson EA, Fujimoto JG. Quantification of nerve fiber layer thickness in normal and glaucomatous eyes using optical coherence tomography. Arch Ophthalmol 1995; 113(5):586-596. https://doi.org/10.1001/archopht.1995.01100050054031.Стоюхина А.С., Будзинская М.В., Стоюхин С.Г., Асламазова А.Э. Оптическая когерентная томография-ангиография в офтальмоонкологии. Вестник офтальмологии 2019; 135(1):104-111. https://doi.org/ 10.17116/oftalma2019135011104Stoyuhina AS, Budzinskaya MV, Stoyuhin SG, Aslamazova AE. Optical coherence tomography-angiography in ophthalmology. Vestnik oftal’mologii 2019; 135(1):104-111. https://doi.org/ 10.17116/oftalma2019135011104Wojtkowski M, Leitgeb R, Kowalczyk A, Bajraszewski T, Fercher AF. In vivo human retinal imaging by Fourier domain optical coherence tomography. J Biomed Opt 2002; 7(3):457-463. https://doi.org/10.1117/1.1482379.Wojtkowski M, Leitgeb R, Kowalczyk A, Bajraszewski T, Fercher AF. In vivo human retinal imaging by Fourier domain optical coherence tomography. J Biomed Opt 2002; 7(3):457-463. https://doi.org/10.1117/1.1482379.Garas A, Vargha P, Hollo G. Reproducibility of retinal nerve fiber layer and macular thickness measurement with the RTVue-100 optical coherence tomograph. Ophthalmology 2010; 117(4):738-746. https://doi.org/10.1016/j.ophtha.2009.08.039.Garas A, Vargha P, Hollo G. Reproducibility of retinal nerve fiber layer and macular thickness measurement with the RTVue-100 optical coherence tomograph. Ophthalmology 2010; 117(4):738-746. https://doi.org/10.1016/j.ophtha.2009.08.039.Kim JS, Ishikawa H, Sung KR, Xu J, Wollstein G, Bilonick RA, Gabriele ML, Kagemann L, Duker JS, Fujimoto JG, Schuman JS. Retinal nerve fibre layer thickness measurement reproducibility improved with spectral domain optical coherence tomography. Br J Ophthalmol 2009; 93(8):1057-1063. https://doi.org/10.1136/bjo.2009.157875.Kim JS, Ishikawa H, Sung KR, Xu J, Wollstein G, Bilonick RA, Gabriele ML, Kagemann L, Duker JS, Fujimoto JG, Schuman JS. Retinal nerve fibre layer thickness measurement reproducibility improved with spectral domain optical coherence tomography. Br J Ophthalmol 2009; 93(8):1057-1063. https://doi.org/10.1136/bjo.2009.157875.Medeiros FA, Zangwill LM, Bowd C, Vessani RM, Susanna R, Jr., Weinreb RN. Evaluation of retinal nerve fiber layer, optic nerve head, and macular thickness measurements for glaucoma detection using optical coherence tomography. Am J Ophthalmol 2005; 139(1):44-55. https://doi.org/10.1016/j.ajo.2004.08.069.Medeiros FA, Zangwill LM, Bowd C, Vessani RM, Susanna R, Jr., Weinreb RN. Evaluation of retinal nerve fiber layer, optic nerve head, and macular thickness measurements for glaucoma detection using optical coherence tomography. Am J Ophthalmol 2005; 139(1):44-55. https://doi.org/10.1016/j.ajo.2004.08.069.Budenz DL, Michael A, Chang RT, McSoley J, Katz J. Sensitivity and specificity of the StratusOCT for perimetric glaucoma. Ophthalmology 2005; 112(1):3-9. https://doi.org/10.1016/j.ophtha.2004.06.039.Budenz DL, Michael A, Chang RT, McSoley J, Katz J. Sensitivity and specificity of the StratusOCT for perimetric glaucoma. Ophthalmology 2005; 112(1):3-9. https://doi.org/10.1016/j.ophtha.2004.06.039.Budenz DL, Chang RT, Huang X, Knighton RW, Tielsch JM. Reproducibility of retinal nerve fiber thickness measurements using the stratus OCT in normal and glaucomatous eyes. Invest Ophthalmol Vis Sci 2005; 46(7):2440-2443. https://doi.org/10.1167/iovs.04-1174.Budenz DL, Chang RT, Huang X, Knighton RW, Tielsch JM. Reproducibility of retinal nerve fiber thickness measurements using the stratus OCT in normal and glaucomatous eyes. Invest Ophthalmol Vis Sci 2005; 46(7):2440-2443. https://doi.org/10.1167/iovs.04-1174.Chang RT, Knight OJ, Feuer WJ, Budenz DL. Sensitivity and specificity of time-domain versus spectral-domain optical coherence tomography in diagnosing early to moderate glaucoma. Ophthalmology 2009; 116(12):2294-2299. https://doi.org/10.1016/j.ophtha.2009.06.012.Chang RT, Knight OJ, Feuer WJ, Budenz DL. Sensitivity and specificity of time-domain versus spectral-domain optical coherence tomography in diagnosing early to moderate glaucoma. Ophthalmology 2009; 116(12):2294-2299. https://doi.org/10.1016/j.ophtha.2009.06.012.Vizzeri G, Balasubramanian M, Bowd C, Weinreb RN, Medeiros FA, Zangwill LM. Spectral domain-optical coherence tomography to detect localized retinal nerve fiber layer defects in glaucomatous eyes. Opt Express 2009; 17(5):4004-4018. https://doi.org/10.1364/oe.17.004004.Vizzeri G, Balasubramanian M, Bowd C, Weinreb RN, Medeiros FA, Zangwill LM. Spectral domain-optical coherence tomography to detect localized retinal nerve fiber layer defects in glaucomatous eyes. Opt Express 2009; 17(5):4004-4018. https://doi.org/10.1364/oe.17.004004.Park SB, Sung KR, Kang SY, Kim KR, Kook MS. Comparison of glauco- ma diagnostic Capabilities of Cirrus HD and Stratus optical coherence tomography. Arch Ophthalmol 2009; 127(12):1603-1609. https://doi.org/10.1001/archophthalmol.2009.296.Park SB, Sung KR, Kang SY, Kim KR, Kook MS. Comparison of glauco- ma diagnostic Capabilities of Cirrus HD and Stratus optical coherence tomography. Arch Ophthalmol 2009; 127(12):1603-1609. https://doi.org/10.1001/archophthalmol.2009.296.Hung KC, Wu PC, Poon YC, Chang HW, Lai IC, Tsai JC, Lin PW, Teng MC. Macular Diagnostic Ability in OCT for Assessing Glaucoma in High Myopia. Optom Vis Sci 2016; 93(2):126-135. https://doi.org/10.1097/OPX.0000000000000776.Hung KC, Wu PC, Poon YC, Chang HW, Lai IC, Tsai JC, Lin PW, Teng MC. Macular Diagnostic Ability in OCT for Assessing Glaucoma in High Myopia. Optom Vis Sci 2016; 93(2):126-135. https://doi.org/10.1097/OPX.0000000000000776.Chua J, Tan B, Ke M, Schwarzhans F, Vass C, Wong D, Nongpiur ME, Wei Chua MC, Yao X, Cheng CY, Aung T, Schmetterer L. Diagnostic Ability of Individual Macular Layers by Spectral-Domain OCT in Different Stages of Glaucoma. Ophthalmol Glaucoma 2020; 3(5):314-326. https://doi.org/10.1016/j.ogla.2020.04.003.Chua J, Tan B, Ke M, Schwarzhans F, Vass C, Wong D, Nongpiur ME, Wei Chua MC, Yao X, Cheng CY, Aung T, Schmetterer L. Diagnostic Ability of Individual Macular Layers by Spectral-Domain OCT in Different Stages of Glaucoma. Ophthalmol Glaucoma 2020; 3(5):314-326. https://doi.org/10.1016/j.ogla.2020.04.003.Morales-Fernandez L, Jimenez-Santos M, Martinez-de-la-Casa JM, Sanchez-Jean R, Nieves M, Saenz-Frances F, Garcia-Saenz S, Perucho L, Gomez-de-Liano R, Garcia-Feijoo J. Diagnostic capacity of SD-OCT segmented ganglion cell complex versus retinal nerve fiber layer analysis for congenital glaucoma. Eye (Lond) 2018; 32(8):1338-1344. https://doi.org/10.1038/s41433-018-0077-4.Morales-Fernandez L, Jimenez-Santos M, Martinez-de-la-Casa JM, Sanchez-Jean R, Nieves M, Saenz-Frances F, Garcia-Saenz S, Perucho L, Gomez-de-Liano R, Garcia-Feijoo J. Diagnostic capacity of SD-OCT segmented ganglion cell complex versus retinal nerve fiber layer anal- ysis for congenital glaucoma. Eye (Lond) 2018; 32(8):1338-1344. https://doi.org/10.1038/s41433-018-0077-4.Aksoy FE, Altan C, Yilmaz BS, Yilmaz I, Tunc U, Kesim C, Kocamaz M, Pasaoglu I. A comparative evaluation of segmental analysis of macu- lar layers in patients with early glaucoma, ocular hypertension, and healthy eyes. J Fr Ophtalmol 2020; 43(9):869-878. https://doi.org/10.1016/j.jfo.2019.12.020.Aksoy FE, Altan C, Yilmaz BS, Yilmaz I, Tunc U, Kesim C, Kocamaz M, Pasaoglu I. A comparative evaluation of segmental analysis of macu- lar layers in patients with early glaucoma, ocular hypertension, and healthy eyes. J Fr Ophtalmol 2020; 43(9):869-878. https://doi.org/10.1016/j.jfo.2019.12.020.Leung CK, Cheung CY, Weinreb RN, Qiu K, Liu S, Li H, Xu G, Fan N, Pang CP, Tse KK, Lam DS. Evaluation of retinal nerve fiber layer pro- gression in glaucoma: a study on optical coherence tomography guided progression analysis. Invest Ophthalmol Vis Sci 2010; 51(1):217-222. https://doi.org/10.1167/iovs.09-3468.Leung CK, Cheung CY, Weinreb RN, Qiu K, Liu S, Li H, Xu G, Fan N, Pang CP, Tse KK, Lam DS. Evaluation of retinal nerve fiber layer pro- gression in glaucoma: a study on optical coherence tomography guided progression analysis. Invest Ophthalmol Vis Sci 2010; 51(1):217-222. https://doi.org/10.1167/iovs.09-3468.Nguyen AT, Greenfield DS, Bhakta AS, Lee J, Feuer WJ. Detecting Glaucoma Progression Using Guided Progression Analysis with OCT and Visual Field Assessment in Eyes Classified by International Classification of Disease Severity Codes. Ophthalmol Glaucoma 2019; 2(1):36-46. https://doi.org/10.1016/j.ogla.2018.11.004.Nguyen AT, Greenfield DS, Bhakta AS, Lee J, Feuer WJ. Detecting Glaucoma Progression Using Guided Progression Analysis with OCT and Visual Field Assessment in Eyes Classified by International Clas- sification of Disease Severity Codes. Ophthalmol Glaucoma 2019; 2(1):36-46. https://doi.org/10.1016/j.ogla.2018.11.004.Leung CK, Yu M, Weinreb RN, Lai G, Xu G, Lam DS. Retinal nerve fiber layer imaging with spectral-domain optical coherence tomography: patterns of retinal nerve fiber layer progression. Ophthalmology 2012; 119(9):1858-1866. https://doi.org/10.1016/j.ophtha.2012.03.044. 58. Sung KR, Sun JH, Na JH, Lee JY, Lee Y. Progression detection capability of macular thickness in advanced glaucomatous eyes. Ophthalmology 2012; 119(2):308-313. https://doi.org/10.1016/j.ophtha.2011.08.022.Leung CK, Yu M, Weinreb RN, Lai G, Xu G, Lam DS. Retinal nerve fiber layer imaging with spectral-domain optical coherence tomography: patterns of retinal nerve fiber layer progression. Ophthalmology 2012; 119(9):1858-1866. https://doi.org/10.1016/j.ophtha.2012.03.044. 58. Sung KR, Sun JH, Na JH, Lee JY, Lee Y. Progression detection capability of macular thickness in advanced glaucomatous eyes. Ophthalmology 2012; 119(2):308-313. https://doi.org/10.1016/j.ophtha.2011.08.022.Moghimi S, Bowd C, Zangwill LM, Penteado RC, Hasenstab K, Hou H, Ghahari E, Manalastas PIC, Proudfoot J, Weinreb RN. Measurement Floors and Dynamic Ranges of OCT and OCT Angiography in Glau- coma. Ophthalmology 2019; 126(7):980-988. https://doi.org/10.1016/j.ophtha.2019.03.003.Moghimi S, Bowd C, Zangwill LM, Penteado RC, Hasenstab K, Hou H, Ghahari E, Manalastas PIC, Proudfoot J, Weinreb RN. Measurement Floors and Dynamic Ranges of OCT and OCT Angiography in Glau- coma. Ophthalmology 2019; 126(7):980-988. https://doi.org/10.1016/j.ophtha.2019.03.003.Mwanza JC, Sayyad FE, Budenz DL. Choroidal thickness in unilateral advanced glaucoma. Invest Ophthalmol Vis Sci 2012; 53(10):6695-6701. https://doi.org/10.1167/iovs.12-10388.Mwanza JC, Sayyad FE, Budenz DL. Choroidal thickness in unilateral advanced glaucoma. Invest Ophthalmol Vis Sci 2012; 53(10):6695-6701. https://doi.org/10.1167/iovs.12-10388.Li L, Bian A, Zhou Q, Mao J. Peripapillary choroidal thickness in both eyes of glaucoma patients with unilateral visual field loss. Am J Ophthalmol 2013; 156(6):1277-1284 e1271. https://doi.org/10.1016/j.ajo.2013.07.011.Li L, Bian A, Zhou Q, Mao J. Peripapillary choroidal thickness in both eyes of glaucoma patients with unilateral visual field loss. Am J Oph- thalmol 2013; 156(6):1277-1284 e1271. https://doi.org/10.1016/j.ajo.2013.07.011.Chen CL, Bojikian KD, Gupta D, Wen JC, Zhang Q, Xin C, Kono R, Mudumbai RC, Johnstone MA, Chen PP, Wang RK. Optic nerve head perfusion in normal eyes and eyes with glaucoma using optical coher- ence tomography-based microangiography. Quant Imaging Med Surg 2016; 6(2):125-133. https://doi.org/10.21037/qims.2016.03.05.Chen CL, Bojikian KD, Gupta D, Wen JC, Zhang Q, Xin C, Kono R, Mudumbai RC, Johnstone MA, Chen PP, Wang RK. Optic nerve head perfusion in normal eyes and eyes with glaucoma using optical coher- ence tomography-based microangiography. Quant Imaging Med Surg 2016; 6(2):125-133. https://doi.org/10.21037/qims.2016.03.05.Chen CL, Zhang A, Bojikian KD, Wen JC, Zhang Q, Xin C, Mudum- bai RC, Johnstone MA, Chen PP, Wang RK. Peripapillary Retinal Nerve Fiber Layer Vascular Microcirculation in Glaucoma Using Optical Coherence Tomography-Based Microangiography. Invest Ophthalmol Vis Sci 2016; 57(9):OCT475-485. https://doi.org/10.1167/iovs.15-18909.Chen CL, Zhang A, Bojikian KD, Wen JC, Zhang Q, Xin C, Mudumbai RC, Johnstone MA, Chen PP, Wang RK. Peripapillary Retinal Nerve Fiber Layer Vascular Microcirculation in Glaucoma Using Optical Coherence Tomography-Based Microangiography. Invest Ophthalmol Vis Sci 2016; 57(9):OCT475-485. https://doi.org/10.1167/iovs.15-18909.Kwon J, Choi J, Shin JW, Lee J, Kook MS. Alterations of the Foveal Avascular Zone Measured by Optical Coherence Tomography Angiography in Glaucoma Patients With Central Visual Field Defects. Invest Ophthalmol Vis Sci 2017; 58(3):1637-1645. https://doi.org/10.1167/iovs.16-21079.Kwon J, Choi J, Shin JW, Lee J, Kook MS. Alterations of the Foveal Avascular Zone Measured by Optical Coherence Tomography Angiog- raphy in Glaucoma Patients With Central Visual Field Defects. Invest Ophthalmol Vis Sci 2017; 58(3):1637-1645. https://doi.org/10.1167/iovs.16-21079.Braaf B, Vermeer KA, Vienola KV, de Boer JF. Angiography of the retina and the choroid with phase-resolved OCT using interval-optimized backstitched B-scans. Opt Express 2012; 20(18):20516-20534. https://doi.org/10.1364/OE.20.020516.Braaf B, Vermeer KA, Vienola KV, de Boer JF. Angiography of the retina and the choroid with phaseresolved OCT using interval-optimized backstitched B-scans. Opt Express 2012; 20(18):20516-20534. https://doi.org/10.1364/OE.20.020516.Liu L, Jia Y, Takusagawa HL, Pechauer AD, Edmunds B, Lombardi L, Davis E, Morrison JC, Huang D. Optical Coherence Tomography Angiography of the Peripapillary Retina in Glaucoma. JAMA Ophthalmol 2015; 133(9):1045-1052. https://doi.org/10.1001/jamaophthalmol.2015.2225.Liu L, Jia Y, Takusagawa HL, Pechauer AD, Edmunds B, Lombardi L, Davis E, Morrison JC, Huang D. Optical Coherence Tomography Angiography of the Peripapillary Retina in Glaucoma. JAMA Ophthalmol 2015; 133(9):1045-1052. https://doi.org/10.1001/jamaophthalmol.2015.2225.Jia Y, Wei E, Wang X, Zhang X, Morrison JC, Parikh M, Lombardi LH, Gattey DM, Armour RL, Edmunds B, Kraus MF, Fujimoto JG, Huang D. Optical coherence tomography angiography of optic disc perfusion in glaucoma. Ophthalmology 2014; 121(7):1322-1332. https://doi.org/10.1016/j.ophtha.2014.01.021.Jia Y, Wei E, Wang X, Zhang X, Morrison JC, Parikh M, Lombardi LH, Gattey DM, Armour RL, Edmunds B, Kraus MF, Fujimoto JG, Huang D. Optical coherence tomography angiography of optic disc perfusion in glaucoma. Ophthalmology 2014; 121(7):1322-1332. https://doi.org/10.1016/j.ophtha.2014.01.021.Jia Y, Morrison JC, Tokayer J, Tan O, Lombardi L, Baumann B, Lu CD, Choi W, Fujimoto JG, Huang D. Quantitative OCT angiography of optic nerve head blood flow. Biomed Opt Express 2012; 3(12):3127-3137. https://doi.org/10.1364/BOE.3.003127.Jia Y, Morrison JC, Tokayer J, Tan O, Lombardi L, Baumann B, Lu CD, Choi W, Fujimoto JG, Huang D. Quantitative OCT angiography of optic nerve head blood flow. Biomed Opt Express 2012; 3(12):3127-3137. https://doi.org/10.1364/BOE.3.003127.Bojikian KD, Chen CL, Wen JC, Zhang Q, Xin C, Gupta D, Mudumbai RC, Johnstone MA, Wang RK, Chen PP. Optic Disc Perfusion in Primary Open Angle and Normal Tension Glaucoma Eyes Using Optical Coherence Tomography-Based Microangiography. PLoS One 2016; 11(5):e0154691. https://doi.org/10.1371/journal.pone.0154691.Bojikian KD, Chen CL, Wen JC, Zhang Q, Xin C, Gupta D, Mudumbai RC, Johnstone MA, Wang RK, Chen PP. Optic Disc Perfusion in Primary Open Angle and Normal Tension Glaucoma Eyes Using Optical Coherence Tomography-Based Microangiography. PLoS One 2016; 11(5):e0154691. https://doi.org/10.1371/journal.pone.0154691.Chen HS, Liu CH, Wu WC, Tseng HJ, Lee YS. Optical Coherence Tomography Angiography of the Superficial Microvasculature in the Macular and Peripapillary Areas in Glaucomatous and Healthy Eyes. Invest Ophthalmol Vis Sci 2017; 58(9):3637-3645. https://doi.org/10.1167/iovs.17-21846.Chen HS, Liu CH, Wu WC, Tseng HJ, Lee YS. Optical Coherence Tomography Angiography of the Superficial Microvasculature in the Macular and Peripapillary Areas in Glaucomatous and Healthy Eyes. Invest Ophthalmol Vis Sci 2017; 58(9):3637-3645. https://doi.org/10.1167/iovs.17-21846.Alnawaiseh M, Lahme L, Muller V, Rosentreter A, Eter N. Correla- tion of flow density, as measured using optical coherence tomography angiography, with structural and functional parameters in glaucoma patients. Graefes Arch Clin Exp Ophthalmol 2018; 256(3):589-597. https://doi.org/10.1007/s00417-017-3865-9.Alnawaiseh M, Lahme L, Muller V, Rosentreter A, Eter N. Correlation of flow density, as measured using optical coherence tomography angiography, with structural and functional parameters in glaucoma patients. Graefes Arch Clin Exp Ophthalmol 2018; 256(3):589-597. https://doi.org/10.1007/s00417-017-3865-9.Yarmohammadi A, Zangwill LM, Diniz-Filho A, Suh MH, Manalastas PI, Fatehee N, Yousefi S, Belghith A, Saunders LJ, Medeiros FA, Huang D, Weinreb RN. Optical Coherence Tomography Angiography Vessel Density in Healthy, Glaucoma Suspect, and Glaucoma Eyes. Invest Ophthalmol Vis Sci 2016; 57(9):OCT451-459. https://doi.org/10.1167/iovs.15-18944.Yarmohammadi A, Zangwill LM, Diniz-Filho A, Suh MH, Manalastas PI, Fatehee N, Yousefi S, Belghith A, Saunders LJ, Medeiros FA, Huang D, Weinreb RN. Optical Coherence Tomography Angiography Vessel Density in Healthy, Glaucoma Suspect, and Glaucoma Eyes. Invest Ophthalmol Vis Sci 2016; 57(9):OCT451-459. https://doi.org/10.1167/iovs.15-18944.Yip VCH, Wong HT, Yong VKY, Lim BA, Hee OK, Cheng J, Fu H, Lim C, Tay ELT, Loo-Valdez RG, Teo HY, Lim Ph A, Yip LWL. Optical Coherence Tomography Angiography of Optic Disc and Macula Vessel Density in Glaucoma and Healthy Eyes. J Glaucoma 2019; 28(1):80-87. https://doi.org/10.1097/IJG.0000000000001125.Yip VCH, Wong HT, Yong VKY, Lim BA, Hee OK, Cheng J, Fu H, Lim C, Tay ELT, Loo-Valdez RG, Teo HY, Lim Ph A, Yip LWL. Optical Coherence Tomography Angiography of Optic Disc and Macula Vessel Density in Glaucoma and Healthy Eyes. J Glaucoma 2019; 28(1):80-87. https://doi.org/10.1097/IJG.0000000000001125.Hou H, Moghimi S, Zangwill LM, Shoji T, Ghahari E, Manalastas PIC, Penteado RC, Weinreb RN. Inter-eye Asymmetry of Optical Coherence Tomography Angiography Vessel Density in Bilateral Glaucoma, Glau- coma Suspect, and Healthy Eyes. Am J Ophthalmol 2018; 190:69-77. https://doi.org/10.1016/j.ajo.2018.03.026.Hou H, Moghimi S, Zangwill LM, Shoji T, Ghahari E, Manalastas PIC, Penteado RC, Weinreb RN. Inter-eye Asymmetry of Optical Coherence Tomography Angiography Vessel Density in Bilateral Glaucoma, Glaucoma Suspect, and Healthy Eyes. Am J Ophthalmol 2018; 190:69-77. https://doi.org/10.1016/j.ajo.2018.03.026.Suwan Y, Fard MA, Geyman LS, Tantraworasin A, Chui TY, Rosen RB, Ritch R. Association of Myopia With Peripapillary Perfused Capillary Density in Patients With Glaucoma: An Optical Coherence Tomogra- phy Angiography Study. JAMA Ophthalmol 2018; 136(5):507-513. https://doi.org/10.1001/jamaophthalmol.2018.0776.Suwan Y, Fard MA, Geyman LS, Tantraworasin A, Chui TY, Rosen RB, Ritch R. Association of Myopia With Peripapillary Perfused Capillary Density in Patients With Glaucoma: An Optical Coherence Tomography Angiography Study. JAMA Ophthalmol 2018; 136(5):507-513. https://doi.org/10.1001/jamaophthalmol.2018.0776.Akil H, Chopra V, Al-Sheikh M, Ghasemi Falavarjani K, Huang AS, Sadda SR, Francis BA. Swept-source OCT angiography imaging of the macular capillary network in glaucoma. Br J Ophthalmol 2017; 132(4):515-519. https://doi.org/10.1136/bjophthalmol-2016-309816.Akil H, Chopra V, Al-Sheikh M, Ghasemi Falavarjani K, Huang AS, Sadda SR, Francis BA. Swept-source OCT angiography imaging of the macular capillary network in glaucoma. Br J Ophthalmol 2017; 132(4):515-519. https://doi.org/10.1136/bjophthalmol-2016-309816.Penteado RC, Zangwill LM, Daga FB, Saunders LJ, Manalastas PIC, Shoji T, Akagi T, Christopher M, Yarmohammadi A, Moghimi S, Weinreb RN. Optical Coherence Tomography Angiography Macular Vascular Density Measurements and the Central 10-2 Visual Field in Glau- coma. J Glaucoma 2018; 27(6):481-489. https://doi.org/10.1097/IJG.0000000000000964.Penteado RC, Zangwill LM, Daga FB, Saunders LJ, Manalastas PIC, Shoji T, Akagi T, Christopher M, Yarmohammadi A, Moghimi S, Wein- reb RN. Optical Coherence Tomography Angiography Macular Vascu- lar Density Measurements and the Central 10-2 Visual Field in Glau- coma. J Glaucoma 2018; 27(6):481-489. https://doi.org/10.1097/IJG.0000000000000964.Rao HL, Pradhan ZS, Weinreb RN, Dasari S, Riyazuddin M, Venugopal JP, Puttaiah NK, Rao DAS, Devi S, Mansouri K, Webers CAB. Optical Coherence Tomography Angiography Vessel Density Measurements in Eyes With Primary Open-Angle Glaucoma and Disc Hemorrhage. J Glaucoma 2017; 26(10):888-895. https://doi.org/10.1097/IJG.0000000000000758.Rao HL, Pradhan ZS, Weinreb RN, Dasari S, Riyazuddin M, Venugopal JP, Puttaiah NK, Rao DAS, Devi S, Mansouri K, Webers CAB. Optical Coherence Tomography Angiography Vessel Density Measurements in Eyes With Primary Open-Angle Glaucoma and Disc Hemorrhage. J Glaucoma 2017; 26(10):888-895. https://doi.org/10.1097/IJG.0000000000000758.Triolo G, Rabiolo A, Shemonski ND, Fard A, Di Matteo F, Sacconi R, Bettin P, Magazzeni S, Querques G, Vazquez LE, Barboni P, Bandello F. Optical Coherence Tomography Angiography Macular and Peripapillary Vessel Perfusion Density in Healthy Subjects, Glaucoma Suspects, and Glaucoma Patients. Invest Ophthalmol Vis Sci 2017; 58(13):5713-5722. https://doi.org/10.1167/iovs.17-22865.Triolo G, Rabiolo A, Shemonski ND, Fard A, Di Matteo F, Sacconi R, Bettin P, Magazzeni S, Querques G, Vazquez LE, Barboni P, Bandello F. Optical Coherence Tomography Angiography Macular and Peripapillary Vessel Perfusion Density in Healthy Subjects, Glaucoma Suspects, and Glaucoma Patients. Invest Ophthalmol Vis Sci 2017; 58(13):5713-5722. https://doi.org/10.1167/iovs.17-22865.Shoji T, Zangwill LM, Akagi T, Saunders LJ, Yarmohammadi A, Manalastas PIC, Penteado RC, Weinreb RN. Progressive Macula Vessel Density Loss in Primary Open-Angle Glaucoma: A Longitudinal Study. Am J Ophthalmol 2017; 182:107-117. https://doi.org/10.1016/j.ajo.2017.07.011.Shoji T, Zangwill LM, Akagi T, Saunders LJ, Yarmohammadi A, Manalastas PIC, Penteado RC, Weinreb RN. Progressive Macula Vessel Density Loss in Primary Open-Angle Glaucoma: A Longitudinal Study. Am J Ophthalmol 2017; 182:107-117. https://doi.org/10.1016/j.ajo.2017.07.011.Moghimi S, Zangwill LM, Penteado RC, Hasenstab K, Ghahari E, Hou H, Christopher M, Yarmohammadi A, Manalastas PIC, Shoji T, Bowd C, Weinreb RN. Macular and Optic Nerve Head Vessel Density and Progressive Retinal Nerve Fiber Layer Loss in Glaucoma. Ophthal- mology 2018; 125(11):1720-1728. https://doi.org/10.1016/j.ophtha.2018.05.006.Moghimi S, Zangwill LM, Penteado RC, Hasenstab K, Ghahari E, Hou H, Christopher M, Yarmohammadi A, Manalastas PIC, Shoji T, Bowd C, Weinreb RN. Macular and Optic Nerve Head Vessel Density and Progressive Retinal Nerve Fiber Layer Loss in Glaucoma. Ophthal- mology 2018; 125(11):1720-1728. https://doi.org/10.1016/j.ophtha.2018.05.006.Moghimi S, Hosseini H, Riddle J, Lee GY, Bitrian E, Giaconi J, Caprioli J, Nouri-Mahdavi K. Measurement of optic disc size and rim area with spectral-domain OCT and scanning laser ophthalmoscopy. Invest Ophthalmol Vis Sci 2012; 53(8):4519-4530. https://doi.org/10.1167/iovs.11-8362.Moghimi S, Hosseini H, Riddle J, Lee GY, Bitrian E, Giaconi J, Caprioli J, Nouri-Mahdavi K. Measurement of optic disc size and rim area with spectral-domain OCT and scanning laser ophthalmoscopy. Invest Ophthalmol Vis Sci 2012; 53(8):4519-4530. https://doi.org/10.1167/iovs.11-8362.Stoor K, Karvonen E, Leiviska I, Liinamaa J, Saarela V. Comparison of imaging parameters between OCT, GDx and HRT in the Northern Finland birth cohort eye study. Acta Ophthalmol 2022; 100(5): e1103-e1111. https://doi.org/10.1111/aos.15046.Stoor K, Karvonen E, Leiviska I, Liinamaa J, Saarela V. Comparison of imaging parameters between OCT, GDx and HRT in the Northern Finland birth cohort eye study. Acta Ophthalmol 2022; 100(5): e1103-e1111. https://doi.org/10.1111/aos.15046.Badala F, Nouri-Mahdavi K, Raoof DA, Leeprechanon N, Law SK, Cap- rioli J. Optic disk and nerve fiber layer imaging to detect glaucoma. Am J Ophthalmol 2007;144(5):724-732. https://doi.org/10.1016/j.ajo.2007.07.010.Badala F, Nouri-Mahdavi K, Raoof DA, Leeprechanon N, Law SK, Cap- rioli J. Optic disk and nerve fiber layer imaging to detect glaucoma. Am J Ophthalmol 2007;144(5):724-732. https://doi.org/10.1016/j.ajo.2007.07.010.Karvonen E, Stoor K, Luodonpaa M, Hagg P, Lintonen T, Liinamaa J, Tuulonen A, Saarela V. Diagnostic performance of modern imaging instruments in glaucoma screening. Br J Ophthalmol 2020; 104(10): 1399-1405. https://doi.org/10.1136/bjophthalmol-2019-314795.Karvonen E, Stoor K, Luodonpaa M, Hagg P, Lintonen T, Liinamaa J, Tuulonen A, Saarela V. Diagnostic performance of modern imaging instruments in glaucoma screening. Br J Ophthalmol 2020; 104(10): 1399-1405. https://doi.org/10.1136/bjophthalmol-2019-314795.Zangwill LM, Bowd C, Berry CC, Williams J, Blumenthal EZ, Sanchez-Galeana CA, Vasile C, Weinreb RN. Discriminating between normal and glaucomatous eyes using the Heidelberg Retina Tomograph, GDx Nerve Fiber Analyzer, and Optical Coherence Tomograph. Arch Ophthalmol 2001; 119(7):985-993. https://doi.org/10.1001/archopht.119.7.985.Zangwill LM, Bowd C, Berry CC, Williams J, Blumenthal EZ, Sanchez-Galeana CA, Vasile C, Weinreb RN. Discriminating between normal and glaucomatous eyes using the Heidelberg Retina Tomograph, GDx Nerve Fiber Analyzer, and Optical Coherence Tomograph. Arch Oph- thalmol 2001; 119(7):985-993. https://doi.org/10.1001/archopht.119.7.985.Medeiros FA, Zangwill LM, Bowd C, Weinreb RN. Comparison of the GDx VCC scanning laser polarimeter, HRT II confocal scanning laser ophthalmoscope, and stratus OCT optical coherence tomograph for the detection of glaucoma. Arch Ophthalmol 2004; 122(6):827-837. https://doi.org/10.1001/archopht.122.6.827.Medeiros FA, Zangwill LM, Bowd C, Weinreb RN. Comparison of the GDx VCC scanning laser polarimeter, HRT II confocal scanning laser ophthalmoscope, and stratus OCT optical coherence tomograph for the detection of glaucoma. Arch Ophthalmol 2004; 122(6):827-837. https://doi.org/10.1001/archopht.122.6.827.Sato S, Hirooka K, Baba T, Shiraga F. Comparison of optic nerve head parameters using Heidelberg Retina Tomograph 3 and spectral-domain optical coherence tomography. Clin Exp Ophthalmol 2012; 40(7):721-726. https://doi.org/10.1111/j.1442-9071.2012.02782.x.Sato S, Hirooka K, Baba T, Shiraga F. Comparison of optic nerve head parameters using Heidelberg Retina Tomograph 3 and spectral-domain optical coherence tomography. Clin Exp Ophthalmol 2012; 40(7):721-726. https://doi.org/10.1111/j.1442-9071.2012.02782.x.Moreno-Montanes J, Anton A, Garcia N, Olmo N, Morilla A, Fallon M. Comparison of retinal nerve fiber layer thickness values using Stratus Optical Coherence Tomography and Heidelberg Retina Tomograph-III. J Glaucoma 2009; 18(7):528-534. https://doi.org/10.1097/IJG.0b013e318193c29f.Moreno-Montanes J, Anton A, Garcia N, Olmo N, Morilla A, Fallon M. Comparison of retinal nerve fiber layer thickness values using Stratus Optical Coherence Tomography and Heidelberg Retina Tomograph-III. J Glaucoma 2009; 18(7):528-534. https://doi.org/10.1097/IJG.0b013e318193c29f.Lisboa R, Leite MT, Zangwill LM, Tafreshi A, Weinreb RN, Medeiros FA. Diagnosing preperimetric glaucoma with spectral domain optical coherence tomography. Ophthalmology 2012; 119(11):2261-2269. https://doi.org/10.1016/j.ophtha.2012.06.009.Lisboa R, Leite MT, Zangwill LM, Tafreshi A, Weinreb RN, Medeiros FA. Diagnosing preperimetric glaucoma with spectral domain optical coherence tomography. Ophthalmology 2012; 119(11):2261-2269. https://doi.org/10.1016/j.ophtha.2012.06.009.Medeiros FA, Vizzeri G, Zangwill LM, Alencar LM, Sample PA, Weinreb RN. Comparison of retinal nerve fiber layer and optic disc imaging for diagnosing glaucoma in patients suspected of having the disease. Ophthalmology 2008; 115(8):1340-1346. https://doi.org/10.1016/j.ophtha.2007.11.008.Medeiros FA, Vizzeri G, Zangwill LM, Alencar LM, Sample PA, Wein- reb RN. Comparison of retinal nerve fiber layer and optic disc imaging for diagnosing glaucoma in patients suspected of having the disease. Ophthalmology 2008; 115(8):1340-1346. https://doi.org/10.1016/j.ophtha.2007.11.008.Alencar LM, Zangwill LM, Weinreb RN, Bowd C, Sample PA, Girkin CA, Liebmann JM, Medeiros FA. A comparison of rates of change in neuroretinal rim area and retinal nerve fiber layer thickness in progressive glaucoma. Invest Ophthalmol Vis Sci 2010; 51(7):3531-3539. https://doi.org/10.1167/iovs.09-4350.Alencar LM, Zangwill LM, Weinreb RN, Bowd C, Sample PA, Girkin CA, Liebmann JM, Medeiros FA. A comparison of rates of change in neuro- retinal rim area and retinal nerve fiber layer thickness in progressive glaucoma. Invest Ophthalmol Vis Sci 2010; 51(7):3531-3539. https://doi.org/10.1167/iovs.09-4350.Kim HG, Heo H, Park SW. Comparison of scanning laser polarimetry and optical coherence tomography in preperimetric glaucoma. Optom Vis Sci 2011; 88(1):124-129. https://doi.org/10.1097/OPX.0b013e3181fdef9c.Kim HG, Heo H, Park SW. Comparison of scanning laser polarimetry and optical coherence tomography in preperimetric glaucoma. Optom Vis Sci 2011; 88(1):124-129. https://doi.org/10.1097/OPX.0b013e3181fdef9c.Brusini P, Salvetat ML, Zeppieri M, Tosoni C, Parisi L, Felletti M. Comparison between GDx VCC scanning laser polarimetry and Stratus OCT optical coherence tomography in the diagnosis of chronic glaucoma. Acta Ophthalmol Scand 2006; 84(5):650-655. https://doi.org/10.1111/j.1600-0420.2006.00747.x.Brusini P, Salvetat ML, Zeppieri M, Tosoni C, Parisi L, Felletti M. Comparison between GDx VCC scanning laser polarimetry and Stratus OCT optical coherence tomography in the diagnosis of chronic glaucoma. Acta Ophthalmol Scand 2006; 84(5):650-655. https://doi.org/10.1111/j.1600-0420.2006.00747.x.Horn FK, Mardin CY, Laemmer R, Baleanu D, Juenemann AM, Kruse FE, Tornow RP. Correlation between local glaucomatous visual field defects and loss of nerve fiber layer thickness measured with polarimetry and spectral domain OCT. Invest Ophthalmol Vis Sci 2009; 50(5):1971-1977. https://doi.org/10.1167/iovs.08-2405.Horn FK, Mardin CY, Laemmer R, Baleanu D, Juenemann AM, Kruse FE, Tornow RP. Correlation between local glaucomatous visual field defects and loss of nerve fiber layer thickness measured with polarimetry and spectral domain OCT. Invest Ophthalmol Vis Sci 2009; 50(5):1971-1977. https://doi.org/10.1167/iovs.08-2405.Xu G, Weinreb RN, Leung CKS. Retinal nerve fiber layer progression in glaucoma: a comparison between retinal nerve fiber layer thickness and retardance. Ophthalmology 2013; 120(12):2493-2500. https://doi.org/10.1016/j.ophtha.2013.07.027.Xu G, Weinreb RN, Leung CKS. Retinal nerve fiber layer progression in glaucoma: a comparison between retinal nerve fiber layer thickness and retardance. Ophthalmology 2013; 120(12):2493-2500. https://doi.org/10.1016/j.ophtha.2013.07.027.Lever M, Halfwassen C, Unterlauft JD, Bechrakis NE, Manthey A, Bohm MRR. Retinal nerve fibre layer thickness measurements in childhood glaucoma: the role of scanning laser polarimetry and optical coherence tomography. Graefes Arch Clin Exp Ophthalmol 2021; 259(12):3777-3786. https://doi.org/10.1007/s00417-021-05276-z.Lever M, Halfwassen C, Unterlauft JD, Bechrakis NE, Manthey A, Bohm MRR. Retinal nerve fibre layer thickness measurements in childhood glaucoma: the role of scanning laser polarimetry and optical coherence tomography. Graefes Arch Clin Exp Ophthalmol 2021; 259(12):3777-3786. https://doi.org/10.1007/s00417-021-05276-z.Fallon M, Valero O, Pazos M, Anton A. Diagnostic accuracy of imaging devices in glaucoma: A meta-analysis. Surv Ophthalmol 2017; 62(4): 446-461. https://doi.org/10.1016/j.survophthal.2017.01.001.Fallon M, Valero O, Pazos M, Anton A. Diagnostic accuracy of imaging devices in glaucoma: A meta-analysis. Surv Ophthalmol 2017; 62(4): 446-461. https://doi.org/10.1016/j.survophthal.2017.01.001.

The authors declare that there are no conflicts of interest present.