glaucomaНациональный журнал ГлаукомаNational Journal glaucoma2078-41042311-6862Federal State Budgetary Institution of Science “Krasnov Research Institute of Eye Diseases”10.53432/2078-4104-2024-23-3-45-53glaucoma-535Research ArticleОБЗОРЫ ЛИТЕРАТУРЫLITERATURE REVIEWSИсследование перипапиллярного хориокапиллярного кровотока при глаукоме. Часть 1. Анатомия и патофизиология хориокапиллярного кровотока и его визуализация методом ОКТ-ангиографииPeripapillary choriocapillaris blood flow in glaucoma. Part 1. Anatomy and pathophysiology of choriocapillaris blood flow and its visualization using OCT angiographyhttps://orcid.org/0000-0002-2265-6671КурышеваН. И.KuryshevaN. I.

Д.м.н., профессор, заведующая кафедрой глазных болезней, заведующая консультативно-диагностическим отделом

123098, Москва, ул. Живописная, 46, корп. 8 

123098, Москва, ул. Гамалеи, 15 

Dr. Sci. (Med.), Professor, Head of the Academic Department of Ophthalmology, Head of the Consultative and Diagnostic Department

46-8 Zhivopisnaya St., Moscow, 123098

15 Gamalei St., Moscow, 123098

https://orcid.org/0000-0001-7861-5863КимВ. Ю.KimV. Yu.

Врач-офтальмолог, ассистент кафедры глазных болезней 

123098, Москва, ул. Гамалеи, 15

123098, Москва, ул. Живописная, 46, корп. 8

Ophthalmologist at the Consultative and Diagnostic Department, Assistant Professor at the Academic Department of Ophthalmology

15 Gamalei St., Moscow, 123098

46-8 Zhivopisnaya St., Moscow, 123098

https://orcid.org/0000-0002-8400-2817КимВ. Е.KimV. E.

Врач-офтальмолог, ассистент кафедры глазных болезней 

123098, Москва, ул. Гамалеи, 15

123098, Москва, ул. Живописная, 46, корп. 8

Ophthalmologist at the Consultative and Diagnostic Department, Assistant Professor at the Academic Department of Ophthalmology

15 Gamalei St., Moscow, 123098

46-8 Zhivopisnaya St., Moscow, 123098

kimvaleriya96@gmail.comМедико-биологический университет инноваций и непрерывного образования ФГБУ ГНЦ ФМБЦ им. А.И. Бурназяна ФМБА России ; Центр офтальмологии ФМБА России, ФГБУ ГНЦ ФМБЦ им. А.И. Бурназяна ФМБА РоссииРоссияMedical Biological University of Innovations and Continuing Education, Burnazyan Federal Biophysical Center ; Ophthalmological Center, Burnazyan Federal Biophysical Center, Federal Medical and Biological AgencyRussian FederationЦентр офтальмологии ФМБА России, ФГБУ ГНЦ ФМБЦ им. А.И. Бурназяна ФМБА России ; Медико-биологический университет инноваций и непрерывного образования ФГБУ ГНЦ ФМБЦ им. А.И. Бурназяна ФМБА РоссииРоссияOphthalmological Center, Burnazyan Federal Biophysical Center, Federal Medical and Biological Agency ; Medical Biological University of Innovations and Continuing Education, Burnazyan Federal Biophysical CenterRussian Federation2024190920242334553Copyright © Курышева Н.И., Ким В.Ю., Ким В.Е., 20242024Курышева Н.И., Ким В.Ю., Ким В.Е.Kurysheva N.I., Kim V.Y., Kim V.E.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.glaucomajournal.ru/jour/article/view/535

Патогенетическая роль хориокапиллярного кровотока в прогрессировании глаукомной нейродегенерации давно обсуждается в литературе. Однако визуализировать in vivo глубокие структуры микроциркуляторного русла в перипапиллярной зоне долгое время было проблематично.

Современные методы диагностики, такие как оптическая когерентная томография, особенно SD-OCT и SWEPТ-OCT (SS-OCT) и сканирование в режиме ангиографии, позволяют визуализировать глубокие сосуды глаза, включая хориокапиллярный слой. Это открывает новые возможности для диагностики и отслеживания прогрессирования глаукомы. В обзоре представлены сведения об анатомии хориоидеи, хориокапиллярного слоя, его роль в патогенезе глаукомы, а также последние данные об исследовании указанных структур методами оптической когерентной томографии.

The pathogenic role of choriocapillaris blood flow in the progression of glaucomatous neurodegeneration has long been discussed in the literature. However, in vivo visualization of the deep microcirculatory structures in the peripapillary zone has remained challenging for a long time.

Modern diagnostic methods, such as optical coherence tomography (OCT), particularly spectral domain OCT (SD-OCT), swept-source OCT (SS-OCT), and OCT angiography, now enable the visualization of deep ocular vessels, including the choriocapillaris layer, opening new possibilities for diagnosing and monitoring the progression of glaucoma. This review provides information on the anatomy of the choroid, the choriocapillaris layer, its role in the pathogenesis of glaucoma, as well as the latest methods of studying these structures using optical coherence tomography.

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The authors declare that there are no conflicts of interest present.