glaucomaНациональный журнал ГлаукомаNational Journal glaucoma2078-41042311-6862Federal State Budgetary Institution of Science “Krasnov Research Institute of Eye Diseases”glaucoma-76Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEW OF LITERATUREВозрастные изменения структуры и биомеханических свойств фиброзной оболочки глаза (обзор зарубежной литературы). Сообщение 1. Структурные измененияAge-related changes in the structural and biomechanical properties of the fibrous membrane of the eye (review of foreign literature). Report 1. Structural changesПетровС. Ю.PetrovS. Yu.post@glaucomajournal.ruАнтоновА. А.AntonovA. A.noemail@neicon.ruНовиковИ. А.NovikovI. A.noemail@neicon.ruРещиковаВ. С.ReshchikovaV. S.noemail@neicon.ruПахомоваН. А.PahomovaN. A.noemail@neicon.ruФГБНУ «НИИ глазных болезней»РоссияThe Scientific Research Institute of Eye DiseasesRussian Federation2015170120171438086Copyright © Петров С.Ю., Антонов А.А., Новиков И.А., Рещикова В.С., Пахомова Н.А., 20172017Петров С.Ю., Антонов А.А., Новиков И.А., Рещикова В.С., Пахомова Н.А.Petrov S.Y., Antonov A.A., Novikov I.A., Reshchikova V.S., Pahomova N.A.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.glaucomajournal.ru/jour/article/view/76

Роговица и склера формируют фиброзную оболочку глаза, способную противостоять внешним и внутренним воздействиям и поддерживать форму глазного яблока. Функционирование данных оболочек связано с их структурными особенностями и биомеханическими свойствами, изменение которых с возрастом сказывается на способности выполнять защитную и опорную функции и является прямой или косвенной причиной ряда глазных болезней. Структурные изменения фиброзной оболочки глаза связаны в первую очередь с нарушением организации волокон коллагена, эластина и протеогликанов, которые составляют основу стромы роговицы и склеры. Происходит изменение организации фибриллярных компонентов и увеличение количества поперечных сшивок. Структурные изменения соединительной ткани глаза отражаются на ее функциональном состоянии, в первую очередь на вязкоупругих свойствах роговицы и склеры. Общей тенденцией возрастных изменений фиброзной оболочки глаза, по данным зарубежных исследователей, является увеличение жесткости и снижение вязкоэластических показателей.

The sclera and cornea form the fibrous tunic of the eye which resists external and internal actions and maintains the shape of the eyeball. The functioning of these tunics is associated with their structural and biomechanical properties. Age-related changes of these properties affect protective and supporting functions of the sclera and cornea thus being direct or indirect cause of many ocular disorders. Structural changes of the fibrous tunic of the eye primarily consist in the disorientation of collagen, elastin, and proteoglycan fibers which are the basis of corneal and scleral stroma. Fibrils are disoriented, the number of cross-link bridges increases. Structural changes of ocular connective tissue affect its functionality, i.e., viscoelastic properties of the cornea and sclera. According to the foreign authors, a common tendency of age-related changes of the fibrous tunic of the eye is its stiffening and decrease in viscoelastic properties.

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The authors declare that there are no conflicts of interest present.