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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">glaucoma</journal-id><journal-title-group><journal-title xml:lang="ru">Национальный журнал Глаукома</journal-title><trans-title-group xml:lang="en"><trans-title>National Journal glaucoma</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-4104</issn><issn pub-type="epub">2311-6862</issn><publisher><publisher-name>Federal State Budgetary Institution of Science “Krasnov Research Institute of Eye Diseases”</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">glaucoma-8</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW OF LITERATURE</subject></subj-group></article-categories><title-group><article-title>Влияние кераторефракционной хирургии на результаты сканирующей лазерной поляриметрии</article-title><trans-title-group xml:lang="en"><trans-title>Influence of corneal refractive surgery on scanning laser polarimetry</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Холло</surname><given-names>Габор</given-names></name><name name-style="western" xml:lang="en"><surname>Hollo</surname><given-names>Gábor</given-names></name></name-alternatives><email xlink:type="simple">hg@szem1.sote.hu</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Университета им. Земмельвейса</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Semmelweis University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>17</day><month>01</month><year>2017</year></pub-date><volume>13</volume><issue>1</issue><fpage>56</fpage><lpage>58</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Холло Г., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Холло Г.</copyright-holder><copyright-holder xml:lang="en">Hollo G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.glaucomajournal.ru/jour/article/view/8">https://www.glaucomajournal.ru/jour/article/view/8</self-uri><abstract><p>На сегодняшний день использование современных методов медицинской визуализации является необходимым условием получения более точных результатов диагностики глаукомы. Одним из таких методов является сканирующая лазерная поляриметрия (СЛП), разработанная для оценки одного из наиболее важных критериев диагностики глаукомного процесса - толщины слоя нервных волокон (СНВ) в перипапиллярной зоне сетчатки и автоматического сравнения результатов с показателями нормы. Измерение толщины СНВ с помощью санирующей лазерной поляриметрии основано на так называемом эффекте ретардации - замедлении поляризованного пучка света. Параллельная структура микротрубочек в нервных волокнах обеспечивает эффект двойного лучепреломления - расщепления проходящей световой волны на две части, поляризованные в двух взаимно перпендикулярных плоскостях, проходящие СНВ с различной скоростью. Величина световой задержки определяется детектором сканирующего лазерного поляриметра и преобразуется в толщину СНВ в микронах. Согласно результатам исследований, хирургические вмешательства на роговице, такие как LASIK, могут клинически значимо изменять величину световой задержки. В таких случаях бывает необходимо применение методов нейтрализации погрешностей измерения во избежание неверного толкования результатов исследования. С увеличением частоты рефракционных хирургических вмешательств для коррекции аметропии, в том числе у молодых людей, у которых в будущем может развиться глаукома, эта проблема приобрела большую клиническую значимость. Благодаря использованию нового поколения лазерных поляриметров GDx-VCC с переменным роговичным компенсатором (VCC - variable corneal compensator) было установлено, что изменение световой задержки после LASIK является артефактом, а не признаком повреждения нервных волокон. Недавно было разработано новое оборудование GDx-ECC, оснащенное усиленным роговичным компенсатором (ЕСС - enhanced corneal compensation). Оно было протестировано несколькими исследовательскими группами и показало большую точность результатов, чем предшествующий ему поляриметр GDx-VCC. Таким образом, можно предположить, что на сегодняшний день именно GDx-ECC лучше всего подходит для компенсации изменений в световой задержке после LASIK и долгосрочного наблюдения за пациентами после рефракционной хирургии.</p></abstract><trans-abstract xml:lang="en"><p>In order to improve the accuracy of glaucoma diagnostics, the use of the modern imaging technologies in routine practice has become necessary. Scanning laser polarimetry (SLP) is one of the widely-used modern imaging technologies. It was developed to measure the thickness of the retinal nerve fibre layer (RNFLT) around the optic nerve head, and to automatically compare the results with the corresponding normative database reference values. The method is based on retardation (slowing down) of the polarized illuminating laser light of the instrument along one axis (“slow axis”) by the birefringent retinal ganglion cell axons. Certain surgical interventions which involve the corneal tissue (such as LASIK) may have clinically significant influence on the corneal retardation, which may potentially lead to misinterpretation of the results. Since corneal refractive surgery has become a widely-used method to correct for ametropia, and many young people, who in future may develop glaucoma, undergo different types of refractive surgery, this issue gained great clinical significance. Following the introduction of GDx-VCC, the next generation of the GDx devices, the influence of corneal retardation became easily manageable, which helped to confirm that the virtual decrease of the post-LASIK polarimetric RNFLT was an artifact, and was not the sign of true RNFLT damage. Recently a new polarimetric software version (enhanced corneal compensation, GDx-ECC) was developed and investigated by different research groups for its ability to remove the LASlK-induced corneal retardation artifacts, proving the new method to be more accurate than GDx-VCC. It all led to a conclusion that since GDx-ECC is able to neutralize changes of corneal retardation induced by LASIK, this software may be even more suitable to long-term follow-up of eyes which undergo corneal refractive surgery.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>scanning laser polarimetry</kwd><kwd>glaucoma</kwd><kwd>retardation</kwd><kwd>LASIK</kwd><kwd>GDx</kwd><kwd>сканирующая лазерная поляриметрия</kwd><kwd>глаукома</kwd><kwd>рефракционная хирургия</kwd><kwd>GDx-VCC</kwd><kwd>GDx-ECC</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Choplin N.T., Schallhorn S.C. 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