Ганглиозные клетки сетчатки: возможности нейропротекции при глаукоме
Аннотация
Нейропротекторная терапия является современным и одним из наиболее перспективных направлений в лечении глаукомы. Эта стратегия подразумевает защиту сетчатки, а также волокон зрительного нерва от повреждающего действия различных факторов. Клеточная терапия постепенно находит практическое применение почти во всех областях клинической медицины, в том числе и в офтальмологии. Считается, что положительное влияние трансплантации клеток обусловлено нескольки- ми механизмами, одним из которых является трофический, поэтому одним из важных аспектов нейропротекции при глаукоме является коррекция метаболического стресса клеток сетчатки.
В обзоре анализируется современное состояние вопроса изучения ганглиозных клеток сетчатки как мишени для терапии глаукомы, дается представление о новых подходах к лечению этого заболевания с использованием клеточных технологий на основе стратегии нейропротекции.
Об авторах
А. Н. Габашвили
ФГБНУ «Научно-исследовательский институт глазных болезней»
Россия
Россия
к.б.н., научный сотрудник лаборатории фундаментальных исследований в офтальмологии,
119021, Москва, ул. Россолимо, 11А, Б
В. П. Еричев
ФГБНУ «Научно-исследовательский институт глазных болезней»
Россия
Россия
д.м.н., профессор, руководитель отдела глаукомы,
119021, Москва, ул. Россолимо, 11А, Б
Т. В. Нестерова
ФГБНУ «Научно-исследовательский институт глазных болезней»
Россия
Россия
лаборант-исследователь лаборатории фундаментальных исследований в офтальмологии,
119021, Москва, ул. Россолимо, 11А, Б
А. М. Суббот
ФГБНУ «Научно-исследовательский институт глазных болезней»
Россия
Россия
к.м.н., старший научный сотрудник лаборатории фундаментальных исследований в офтальмологии,
119021, Москва, ул. Россолимо, 11А, Б
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Рецензия
Для цитирования:
Габашвили А.Н., Еричев В.П., Нестерова Т.В., Суббот А.М. Ганглиозные клетки сетчатки: возможности нейропротекции при глаукоме. Национальный журнал Глаукома. 2017;16(2):74-81.
For citation:
Gabashvili A.N., Erichev V.P., Nesterova T.N., Subbot A.M. Retinal ganglion cells: potentiality for neuroprotective glaucoma treatment. National Journal glaucoma. 2017;16(2):74-81. (In Russ.)
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