Prediction of disease duration and age of patients with different primary open-angle glaucoma changes
Abstract
PURPOSE: To find out the expected duration of the disease and age of patients with different primary open-angle glaucoma changes. METHODS: The study protocol included data from 120 patients (50 males (41.7%), 70 females (58.3%)); 189 eyes; 102 right eyes; 87 left eyes). The first study group (28 patients, 44 eyes) comprised patients with suspected glaucoma. The second group (53 patients, 84 eyes) consisted of patients with early glaucoma changes. The third group (21 patients, 33 eyes) included patients with advanced glaucoma changes. The forth group (18 patients, 28 eyes) comprised patients with terminal glaucoma. The mean age of the patients was 61.6 (58.4; 66.9) years at the time of diagnosis and 66.9 (63.4; 72.8) years at the endpoint visit in 2013. In all cases the diagnosis was made according to the differential diagnosis system and was proved by special diagnostic techniques. The database included data from 3 qualified examinations as well as tonometry and static automatic perimetry results. RESULTS: The expected mean age of the patients at the moment of total vision loss was 75.1 years. The period, during which patients developed blindness, was limited to 6.1 years. Mean age of the patients at the time of possible glaucoma development was 59.58 (56.14; 64.36) years. The disease itself could have developed within -3.24 (-5.38; -1.2) years prior to the diagnosis. CONCLUSION: Glaucoma diagnostic research should be focused on the age group of 55-60 years. The degree of IOP-lowering in patients with advanced glaucoma changes does not correspond with the Russian glaucoma society recommendations, which determines further progression of the disease.
About the Authors
R. V. Avdeev
State Medical Academy
Russian Federation
Russian Federation
A. S. Alexandrov
Mandryka Medicine Clinical Center
Russian Federation
Russian Federation
N. A. Bakunina
Pirogov City Clinical Hospital
Russian Federation
Russian Federation
A. S. Basinsky
Prof. Basynsky Ophthalmology Center
Russian Federation
Russian Federation
E. A. Blyum
Ophthalmology Hospital
Russian Federation
Russian Federation
A. Yu. Brezhnev
State Medical University
Russian Federation
Russian Federation
E. N. Volkov
Bayandin Ophthalmology Hospital
Russian Federation
Russian Federation
I. R. Gazizova
State Medical University
Russian Federation
Russian Federation
A. B. Galimova
Russian Eye and Plastic Surgery Center
Russian Federation
Russian Federation
O. V. Gaponko
Region Clinical Hospital № 2
Russian Federation
Russian Federation
V. V. Garkavenko
Voyno-Yasenetsky State Medical University
Russian Federation
Russian Federation
A. M. Getmanova
Regional Eye Hospital
Russian Federation
Russian Federation
V. V. Gorodnichy
Mandryka Medicine Clinical Center
Russian Federation
Russian Federation
M. S. Gorshkova
Filatov City Clinical Hospital
Russian Federation
Russian Federation
A. A. Gusarevitch
Regional Hospital № 1
Russian Federation
Russian Federation
S. V. Diordiychuk
Mandryka Medicine Clinical Center
Russian Federation
Russian Federation
D. A. Dorofeev
Ophthalmology Hospital № 3
Russian Federation
Russian Federation
S. A. Zhavoronkov
Filatov City Clinical Hospital
Russian Federation
Russian Federation
P. Ch. Zavadsky
State Medical University
Russian Federation
Russian Federation
O. G. Zvereva
Region Clinical Ophthalmology Hospital
Russian Federation
Russian Federation
U. R. Karimov
Region Ophthalmology Hospital
Russian Federation
Russian Federation
A. V. Kulik
«Meditsina» Medical Center
Russian Federation
Russian Federation
A. V. Kuroyedov
Mandryka Medicine Clinical Center; Russian State Medical University
Russian Federation
Russian Federation
S. N. Lanin
Makarov Ophthalmology Clinical Hospital
Russian Federation
Russian Federation
Dzh. N. Lovpache
Helmgoltz State Ophthalmology Institute
Russian Federation
Russian Federation
I. A. Loskutov
Semashko State Ophthalmology Hospital
Russian Federation
Russian Federation
E. V. Molchanova
State Medical Academy
Russian Federation
Russian Federation
V. Yu. Ogorodnikova
Mandryka Medicine Clinical Center
Russian Federation
Russian Federation
O. N. Onufrichuk
City Government Hospital
Russian Federation
Russian Federation
S. Yu. Petrov
Scientific State Ophthalmology Institute
Russian Federation
Russian Federation
Yu. I. Rozhko
State Hospital
Russian Federation
Russian Federation
T. A. Sidenko
City Government Hospital № 5
Russian Federation
Russian Federation
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Review
For citations:
Avdeev R.V., Alexandrov A.S., Bakunina N.A., Basinsky A.S., Blyum E.A., Brezhnev A.Yu., Volkov E.N., Gazizova I.R., Galimova A.B., Gaponko O.V., Garkavenko V.V., Getmanova A.M., Gorodnichy V.V., Gorshkova M.S., Gusarevitch A.A., Diordiychuk S.V., Dorofeev D.A., Zhavoronkov S.A., Zavadsky P.Ch., Zvereva O.G., Karimov U.R., Kulik A.V., Kuroyedov A.V., Lanin S.N., Lovpache D.N., Loskutov I.A., Molchanova E.V., Ogorodnikova V.Yu., Onufrichuk O.N., Petrov S.Yu., Rozhko Yu.I., Sidenko T.A. Prediction of disease duration and age of patients with different primary open-angle glaucoma changes. National Journal glaucoma. 2014;13(2):60-69. (In Russ.)
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