A RETROSPECTIVE ANALYSIS OF THE ROLE OF CONNECTIVE TISSUE IN THE PATHOGENESIS OF GLAUCOMA
https://doi.org/10.25700/NJG.2018.01.11
Abstract
Open-angle glaucoma pathogenesis, which is important for early diagnosis, treatment and prevention of the disease, remains one of the most difficult and important problems of ophthalmology. A significant role in solving this problem belonged to Kuibyshev Glaucoma Research Laboratory, one of the main directions of which was to study the role of connective tissue in primary open-angle glaucoma pathogenesis.
The purpose of this work is to conduct a retrospective analysis of comprehensive morphological studies of the nature of changes in connective tissue of both anterior segment (drainage system) and the posterior segment (optic nerve) performed in the Glaucoma Research Laboratory.
It is noted that growing disorganization of eye drainage system’s connective tissue components, which happens due to glaucoma, is a cause of disturbance of the intraocular fluid circulation. A similar pattern is noted in the connective tissue components of the cribriform plate. The decrease in the density of the connective tissue of the cribriform plate at the beginning of the glaucoma process and thinning of the cribriform plate in later stages are critical signs of changes in connective tissue supporting the optic nerve. The study of the choroid microvasculature in glaucoma showed that the changes in the vessels are secondary to the connective tissue pathology.
About the Author
L. G. Sennova
Samara State Medical University
Russian Federation
Russian Federation
Ph.D., assistant professor
Department of Eye Diseases, Institute of Professional Education
89 Chapaevskaya st., Samara, 443099
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Review
For citations:
Sennova L.G. A RETROSPECTIVE ANALYSIS OF THE ROLE OF CONNECTIVE TISSUE IN THE PATHOGENESIS OF GLAUCOMA. National Journal glaucoma. 2018;17(1):113-116. (In Russ.) https://doi.org/10.25700/NJG.2018.01.11
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