Secondary neovascular glaucoma as the first manifestation of HIV infection: clinical case
Abstract
Secondary neovascular glaucoma can be the first sign of HIV infection. The main pathogenesis of proliferative processes in the iris and anterior chamber angle are HIVassociated angiopathy, which initiates hypoxia, and an imbalance of endothelial factors. Secondary neovascular glaucoma often occurs as a complication of central retinal vein thrombosis in the older age group or a consequence of previous uveitis. Neovascular glaucoma occurring in a young patient may indicate HIV infection. The publication describes a clinical case of secondary neovascular glaucoma in a young patient as the first sign of manifestation of the HIV infection. A 40-year-old patient with laboratory-confirmed HIV infection complained of decreased vision, pain, redness and lacrimation in the left eye. No other systemic signs of HIV infection were detected. Ophthalmological examination revealed a weak uveal reaction and single vessels along the pupillary edge of the iris. The reason of vision decrease was glaucomatous atrophy of the optic nerve due to neovascular glaucoma. One of the methods of surgical treatment of patients with neovascular glaucoma is modified direct cyclocryopexy, its advantage is a low risk of hemorrhagic complications, suppression of neovascularization, adequate hypotensive and analgesic effects. This clinical case illustrates a good hypotensive result in a 4-year follow-up.
About the Authors
T. Yu. MatnenkoRussian Federation
Cand. Sci. (Med.), Associate Professor at the Academic Department of Ophthalmology
12 Lenina St., Omsk, 644099
O. I. Lebedev
Russian Federation
Dr. Sci. (Med.), Professor, Head of the Academic Department of Ophthalmology
12 Lenina St., Omsk, 644099
S. A. Bataeva
Russian Federation
student
12 Lenina St., Omsk, 644099
E. V. Molchanova
Russian Federation
Cand. Sci. (Med.), Associate Professor at the Academic Department of Ophthalmology
12 Lenina St., Omsk, 644099
A. V. Surov
Russian Federation
Cand. Sci. (Med.), Associate Professor at the Academic Department of Ophthalmology
12 Lenina St., Omsk, 644099
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Supplementary files
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For citations:
Matnenko T.Yu., Lebedev O.I., Bataeva S.A., Molchanova E.V., Surov A.V. Secondary neovascular glaucoma as the first manifestation of HIV infection: clinical case. National Journal glaucoma. 2023;22(3):52-59. (In Russ.)