Glaucoma and metabolic syndrome
https://doi.org/10.53432/2078-4104-2024-23-2-107-116
Abstract
Studies in recent years have shown an increase in the prevalence of systemic diseases, some of which may be independent risk factors for the development and progression of glaucoma. Metabolic syndrome (MetS) is currently one of the leading public health problems in the world. Some studies indicate a relationship between MetS and its individual components (in particular, insulin resistance, hyperglycemia, impaired homeostasis, and systemic arterial hypertension) with an increase in intraocular pressure (IOP), ocular hypertension, and the development of primary open-angle glaucoma (POAG). However, no unambiguous conclusions about the role of MetS in the pathogenesis of glaucoma has been established due to the insufficient number of scientific studies on this topic, the differences in their methodology, and the contradictory results. Further research is needed to determine the role and place of MetS in the occurrence and development of POAG, and the prospects for the practical application of this knowledge.
This review presents literature data on the effect of MetS and its individual components on IOP, occurrence and development of glaucoma and several other ophthalmic diseases
About the Authors
A. M. Getmanova
Bryansk Regional Hospital No. 1; Kursk State Medical University
Russian Federation
Russian Federation
ophthalmologist; postgraduate student at the Academic Department of Ophthalmology
86/1 Stanke Dimitrova Ave., Bryansk, 241028
3 Karla Marksa St., Kursk, 305041
A. Yu. Brezhnev
Kursk State Medical University
Russian Federation
Russian Federation
Cand. Sci. (Med.), Associate Professor at the Academic Department of Ophthalmology
3 Karla Marksa St., Kursk, 305041
A. V. Kuroyedov
Mandryka Central Clinical Hospital; Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Dr. Sci. (Med.), Head of the Ophthalmology Сenter; Professor at the Academic Department of Ophthalmology
8A Bolshaya Olenya St., 117997
1 Ostrovityanova St., Moscow, 117997
S. A. Zubasheva
Treatment and Diagnostic Center No. 9
Russian Federation
Russian Federation
ophthalmologist
15/18 Bolshaya Pirogovskaya St., Moscow, 119021
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Getmanova A.M., Brezhnev A.Yu., Kuroyedov A.V., Zubasheva S.A. Glaucoma and metabolic syndrome. National Journal glaucoma. 2024;23(2):107-116. (In Russ.) https://doi.org/10.53432/2078-4104-2024-23-2-107-116
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