Peripapillary choriocapillaris blood flow in glaucoma. Part 1. Anatomy and pathophysiology of choriocapillaris blood flow and its visualization using OCT angiography
https://doi.org/10.53432/2078-4104-2024-23-3-45-53
Abstract
The pathogenic role of choriocapillaris blood flow in the progression of glaucomatous neurodegeneration has long been discussed in the literature. However, in vivo visualization of the deep microcirculatory structures in the peripapillary zone has remained challenging for a long time.
Modern diagnostic methods, such as optical coherence tomography (OCT), particularly spectral domain OCT (SD-OCT), swept-source OCT (SS-OCT), and OCT angiography, now enable the visualization of deep ocular vessels, including the choriocapillaris layer, opening new possibilities for diagnosing and monitoring the progression of glaucoma. This review provides information on the anatomy of the choroid, the choriocapillaris layer, its role in the pathogenesis of glaucoma, as well as the latest methods of studying these structures using optical coherence tomography.
About the Authors
N. I. Kurysheva
Medical Biological University of Innovations and Continuing Education, Burnazyan Federal Biophysical Center ; Ophthalmological Center, Burnazyan Federal Biophysical Center, Federal Medical and Biological Agency
Russian Federation
Russian Federation
Dr. Sci. (Med.), Professor, Head of the Academic Department of Ophthalmology, Head of the Consultative and Diagnostic Department
46-8 Zhivopisnaya St., Moscow, 123098
15 Gamalei St., Moscow, 123098
V. Yu. Kim
Ophthalmological Center, Burnazyan Federal Biophysical Center, Federal Medical and Biological Agency ; Medical Biological University of Innovations and Continuing Education, Burnazyan Federal Biophysical Center
Russian Federation
Russian Federation
Ophthalmologist at the Consultative and Diagnostic Department, Assistant Professor at the Academic Department of Ophthalmology
15 Gamalei St., Moscow, 123098
46-8 Zhivopisnaya St., Moscow, 123098
V. E. Kim
Ophthalmological Center, Burnazyan Federal Biophysical Center, Federal Medical and Biological Agency ; Medical Biological University of Innovations and Continuing Education, Burnazyan Federal Biophysical Center
Russian Federation
Russian Federation
Ophthalmologist at the Consultative and Diagnostic Department, Assistant Professor at the Academic Department of Ophthalmology
15 Gamalei St., Moscow, 123098
46-8 Zhivopisnaya St., Moscow, 123098
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Review
For citations:
Kurysheva N.I., Kim V.Yu., Kim V.E. Peripapillary choriocapillaris blood flow in glaucoma. Part 1. Anatomy and pathophysiology of choriocapillaris blood flow and its visualization using OCT angiography. National Journal glaucoma. 2024;23(3):45-53. (In Russ.) https://doi.org/10.53432/2078-4104-2024-23-3-45-53
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