Preview

National Journal glaucoma

Advanced search

LONG-TERM EFFICIENCY OF THE MICROINVASIVE NONPENETRATING DEEP SCLERECTOMY IN PRIMARY OPEN-ANGLE GLAUCOMA SURGICAL TREATMENT

Abstract

PURPOSE: To estimate long-term efficiency of the microinvasive nonpenetrating deep sclerectomy (MNPDS) in surgical treatment of primary open-angle glaucoma.

MATERIALS AND METHODS: In our clinical research were analysed the clinical and functional condition of 96 primary open-angle glaucoma (POAG) patients (100 eyes) aged 44-84 years before and after MNPDS. Before the operation and in various terms after the operation all patients underwent ophthalmologic examination: visometry, perimetry, intraocular pressure (IOP) measurement, biomicroscopy, gonioscopy, ophthalmoscopy, ocular ultrasound. Mild glaucoma has been diagnosed in 8 eyes, moderate — in 19 eyes, advanced — in 73 eyes. Baseline IOP on hypotensive treatment varied from 24 to 59 mm Hg. Best corrected visual acuity varied from 20/20 to light perception with projection. Anterior chamber angle according to gonioscopy in all cases was open (Grades 3-4, according to Shaffer system) with various extents of intensive pigmentation of the trabecula. Surgical or laser glaucoma surgery had been carried out on 27 eyes prior to our research.

RESULTS: Our research showed that MNPDS is an effective operation for IOP normalization in the majority of patients. In most cases no postoperative complications were registered, and only 2 patients developed ciliochoroidal detachment that demanded a second operation — posterior sclerotomy. Being microinvasive, this operation allows minimizing operational trauma, reducing excessive postoperative scarring, prolonging the hypotensive effect and maintaining the level of visual functions.

About the Authors

V. V. Egorov
The Khabarovsk branch of Sv.Fyodorov’s Eye Microsurgery Federal State Institution; Postgraduate Institute for Public Health Workers
Russian Federation

Med.Sc.D., Professor, Director The Khabarovsk branch of Sv.Fyodorov’s Eye Microsurgery Federal State Institution, Head of Ophthalmologic Department Postgraduate Institute for Public Health Workers

211 Tikhookeanskaya st., Khabarovsk, 680033, 9 Krasnodarskaya st., Khabarovsk, 680009



A. V. Postupaev
The Khabarovsk branch of Sv.Fyodorov’s Eye Microsurgery Federal State Institution
Russian Federation

M.D 

211 Tikhookeanskaya st., Khabarovsk, 680033



References

1. Libman E.S. Present-day positions of the clinical and social ophthalmology. Vestn Oftalmol 2004; 120(1):10‑12. (In Russ.).

2. National Eye Health Program / National Institutes of Health. Available at: htts://www.nei.nih.gov.

3. Kingman S. Glaucoma is second leading cause of blindness globally. Bulletin of the World Health Organization 2004; 82(11): 887-888. doi: /S0042-96862004001100019.

4. Glaucoma. National guidelines] / Ed. E.A. Egorov. Мoscow, GEOTAR-media Publ., 2013; 824 p. (In Russ.).

5. Libman E.S, Shakhova E.V. Blindness and disability due to pathology of the organ of vision in Russia. Vestn Oftalmol 2006; 122(1):35-37. (In Russ.).

6. Rhee D.J. Glaukoma: atlasy po oftalmologii [Glaucoma: atlas of ophthalmology] / Ed. S.E. Avetisov, V.P. Erichev. M., 2010; 472 p. (In Russ.).

7. Fokin V.P. Analysis of primary disability due to eye diseases as dynamically observed in the Russian Federation in 1994-2003 and its specificity in regions and subjects observed recently (2001-2003). Medico-social expert evaluation and rehabilitation 2004; 4:30-34. (In Russ.).

8. Fokin V.P., Semenov A.D., Smutkina L.I. Blindness and poor vision as the cause of disablement in Russian Federation and Republics of the former USSR. Ophthalmosurgery 2005; 2:48-52. (In Russ.).

9. Choplin N.T., Lundy D.C. Atlas of glaucoma, second edition. Abingdon, GB, Informa Healthcare Publ., 2007; 183-199 p.

10. Doshi V., Ying L.M., Azen S.P., Varma R. Sociodemographic, family history, and lifestyle risk factors for open-angle glaucoma and ocular hypertension. Ophthalmology 2008; 115(1):639-647. doi: /10.1016/j.ophtha.2007.05.032.

11. Miglior S., Torri V., Zeyen T. et al. Intercurrent factors associated with the development of open-angle glaucoma in the European glaucoma prevention study. Am J Ophthalmol 2007; 144(2): 266-275. doi: 10.1016/j.ajo.2007.04.040.

12. Suzuki Y., Iwase A., Araie M. et al. Risk factors for open-angle glaucoma in a Japanese population: the Tajimi Study. Ophthalmology 2006; 113(9):1613-1617. doi: 10.1016/j.ophtha.2006.03.059.

13. Libman E.S., Kaleeva E.V., Ryazanov D.P. Comprehensive description of disability in ophthalmology in Russian Federation. Russian ophthalmology online 2012; 5:24-26. Available at: http://www.eyepress.ru/article.aspx?10314 (In Russ.).

14. Fokin V.P., Balalin S.V. Definition of target intraocular pressure in patients with primary open-angle glaucoma. Glaucoma 2007; 4:16-20. (In Russ.)].

15. Egorov E.A., Astakhov Yu.S., Erichev V.P. Nacionalnoe rukovodstvo po glaukome dlya praktikuyushchih vrachei [National glaucoma guidelines for medical practitioners]. Мoscow, GEOTAR-Media Publ., 2015; 456 p. (In Russ.).

16. Egorov E.A., Kuroyedov A.V. Clinical and epidemiological characteristics of glaucoma in CIS and Georgia. Results of multicenter open-label retrospective trials (part 1). RMJ Clinical Ophthalmology 2011; 12(3):97-100. (In Russ.).

17. Egorov E.A., Kuroyedov A.V. Clinical and epidemiological characteristics of glaucoma in CIS and Georgia. Results of multicenter open-label retrospective trials (part 2). RMJ Clinical Ophthalmology 2012; 13(1):19-22. (In Russ.).

18. Kuroedov A.V., Brezhnev A.Yu., Aleksandrov A.S., Ogorodnikova V.Yu. Principles of treatment of early glaucoma: medical therapy vs. surgery (a review). J. Military-Med 2011; 332(5):28-35. (In Russ.).

19. Maksimov I.B., Kuroyedov A.V., Gorodnichiy V.V., Tsalkina E.B. Prognostic value of baseline intraocular pressure in the early postoperative period in patients with primary open-angle glaucoma. J. Military-Med 2006; 327(12):23-25. (In Russ.).

20. Abysheva L.D., Avdeev R.V., Alexandrov A.S. et al. Multicenter study of intraocular pressure levels in patients with moderate and advanced primary open-angle glaucoma. Ophthalmologic vedomosti 2015; 8(1): 43-60. (In Russ.).

21. Abysheva L.D., Aleksandrov A.S., Arapiev M.U. et al. Optimization of treatment and diagnosis in patients with primary open-angle glaucoma. Natsional’nyi zhurnal glaukoma 2016; 15(2):19-34. (In Russ.).

22. Avdeev R.V., Aleksandrov A.S., Bakunina N.A., Basinskii A.S. et al. Model of manifesting and outcomes of primary open-angle glaucoma. Clin Medicine 2014; 92(12):64-72. (In Russ.).

23. Avdeev R.V., Alexandrov A.S., Basinsky A.S., Blyum E.A. et al. Clinical multicenter study of trabeculectomy efficacy. Natsional’nyi zhurnal glaukoma 2013; 12(2):53-55. (In Russ.).

24. Erichev V.P., Petrov S.Yu., Antonov A.A., Volzhanin A.V. International standards for clinical trials of glaucoma surgery. Natsional’nyi zhurnal glaukoma 2016; 15(2):102-108. (In Russ.).

25. Kuroyedov A.V., Ogorodnikova V.Yu. Microdrainage surgery with EX-PRESS drainage device as a firstline surgical choice for moderate and advanced primary openangle glaucoma. Ophthalmology 2010; 7(1):23-28. (In Russ.).

26. Kuroyedov A.V., Ogorodnikova V.Yu. Longterm outcomes of the implantation of Ex-PRESS drainage device in patients with moderate and advanced glaucoma. Ophthalmology 2012; 9(1):38-43 (In Russ.).

27. Egorov E.A., Kuroyedov A.V., Gorodnichiy V.V. et al. Early and long-term outcomes of glaucoma surgery the results of multicenter study in CIS countries. RMJ. Clinical ophthalmology 2017; 1:25-34. (In Russ.). doi: 10.21689/2311-77292017-17-1-25-34.

28. Krasnov M.M. Sinusotomy technique and its variations. Vestn oftalmol 1968; 3:3-9. (In Russ.).

29. Fedorov S.N., Kozlov V.I., Timoshkina N.T. Non-penetrative deep sclerectomy in open-angle glaucoma. Ophthalmosurgery 1989; 3/4:52-55. (In Russ.).

30. Ivanova E.S., Egorova E.V., Shpak A.A., Gorbunova N.Yu. et al. Preclinical diagnostics of the features of the early postoperative period after performing non-fistulizing operations in primary open-angle glaucoma. Ophthalmosurgery 2011; 1:28-33. (In Russ.).

31. Kozlova T.V., Shaposhnikova N.F., Skobeleva V.B., Sokolovskaya Non-penetrating deep sclerectomy: evolution of the method and prospects for development(review). Ophthalmosurgery 2000; 3:39-53. (In Russ.).

32. Takhchidi Kh.P., Ivanov D.I., Bardasov D.B. Follow-up of microinvasive nonpenetrating deep sclerectomy. Ophthalmosurgery 2003; 3:14-17. (In Russ.).

33. Takhchidi Kh.P., Khodjaev N.S., Takhchidi E.K., Ivanova E.S. et. al. Clinical and functional evaluation of IOP value in early postoperative period after non-penetrating deep sclerectomy (NPDS) and microinvasive non-penetrating deep sclerectomy (MNPDS). Glaucoma 2008; 1:20-25. (In Russ.).


Review

For citations:


Egorov V.V., Postupaev A.V. LONG-TERM EFFICIENCY OF THE MICROINVASIVE NONPENETRATING DEEP SCLERECTOMY IN PRIMARY OPEN-ANGLE GLAUCOMA SURGICAL TREATMENT. National Journal glaucoma. 2017;16(4):23-29. (In Russ.)

Views: 1270


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2078-4104 (Print)
ISSN 2311-6862 (Online)