Novel approaches to glaucoma treatment (review of patents)
https://doi.org/10.53432/2078-4104-2021-20-2-72-80
Abstract
One of the priority directions in the development of medical science is activities associated with patenting and licensing. The review analyzes the inventions of new treatment methods of various forms of glaucoma among patents issued in the last 7 years. The search for new approaches to treating the disease continues despite the numerous known methods. The article describes promising medical, laser, microinvasive, surgical and combined methods for the treatment of glaucoma from the 123 new patents issued in the Russian Federation. Novel innovations are presented with design schemes.
The review will be useful to a wide audience. Young specialists can invent, patent, and license their own original method of glaucoma treatment. Surgeons can expand their routine by introducing new technical elements from different methods, testing its effectiveness and safety in everyday practice.
Supporting agencies: The authors express gratitude to Svetlana Magonova, Head of Patent and Licensing Department of the Republican Scientific Centre for Radiation Medicine and Human Ecology, for her valuable support in working on this review.
About the Authors
Yu. I. Razhko
Republican Scientific Centre for Radiation Medicine and Human Ecology
Belarus
Belarus
Cand. Sci. (Med.), Associate Professor of Eye Microsurgery Department
290 Ilyicha St., Gomel, 246040
I. A. Glushnev
Republican Scientific Centre for Radiation Medicine and Human Ecology
Belarus
Belarus
Ophthalmologist
290 Ilyicha St., Gomel, 246040
N. A. Rebenok
Republican Scientific Centre for Radiation Medicine and Human Ecology
Belarus
Belarus
Ophthalmologist of the Glaucoma Office
290 Ilyicha St., Gomel, 246040
A. V. Kuroyedov
Mandryka Central Military Clinical Hospital; Pirogov Russian National Research Medical University, Ophthalmology Department
Russian Federation
Russian Federation
Dr. Sci. (Med.), Professor, Head of the Ophthalmology Department
8A Bolshaya Olenya St., Moscow, 107014;
1 Ostrovityanova St., Moscow, 117997
A. Yu. Brezhnev
Kursk State Medical University
Russian Federation
Russian Federation
Cand. Sci. (Med.), Associate Professor of the Ophthalmology Department
42a Sadovaya St., Kursk, 305041
References
1. Nacional'noe rukovodstvo po glaukome: dlja praktikujushhih vrachej [National glaucoma guidelines: for medical practitioners]. Ed. by E.A. Egorov, V.P. Erichev. Moscow: GEOTAR-Media; 2019. 384 p. (In Russ.) doi.org/10.33029/9704-5442-8-GLA-2020-1-384
2. Kuroedov A.V., Avdeev R.V., Aleksandrov A.S., Bakunina N.A., Basinsky A.S., Blyum E.A. et al. Primary open-angle glaucoma: the age at which the patient and duration of disease which may occur blindness. Medical and Biological Problems of Life. 2014; 2:74-84. (In Russ.)
3. Kuroyedov A.V., Abysheva L.D., Avdeev R.V., Alexandrov A.S., Basinsky A.S., Blyum E.A. et al. Intraocular pressure level in various local hypotensive therapy in primary open-angle glaucoma (multicenter study). Ophthalmology Eastern Europe. 2016; 6(1):27-42. (In Russ.)
4. Avdeev R.V., Alexandrov A.S., Bakunina N.A., Belaya D.A., Brezhnev A.Yu., Volkova N.V. et al. Analysis of variants of hypotensive treatment of patients with primary open-angle glaucoma by results of multicenter study in clinics of six countries. Medical and Biological Problems of Life. 2018; 1(19):95-111. (In Russ.)
5. Yurova O.V., Nazarova G.A., Konchugova T.V., Morozova N.E. Method of treating patients suffering primary open-angle glaucoma. RU patent 2506062. 2012 Dec. 29. (In Russ.)
6. Konovalova O.S., Ponomareva E.Yu., Konovalova N.A., Ponomareva M.N. Method of treatment of glaucomatous optic neuropathy. RU patent 2578953.2015 Apr. 06. (In Russ.)
7. Isakov V.O., Panova I.E. Method of treating open-angle glaucoma. RU patent 2538233. 2013 July 22. (In Russ.)
8. Egorva E.V., Lyubimova T.S., Uzunjan Dz.G., Ivashchenko E.V. Method for laser treatment of primary open-angle glaucoma following minimally invasive nonpenetrating deep sclerectomy. RU patent 2576811. 2014 Dec. 25. (In Russ.)
9. Kozlova E.E., Lyubimova T.S., Glatkova E.V. Method of treating primary open-angle glaucoma after non-penetrating deep sclerectomy on eyes with narrow angle of anterior chamber. RU patent 2718319. 2019 Aug. 21. (In Russ.)
10. Kolpakova O.A., Fabrikantov O.L. Method of selecting parameters of laser exposure in treating far-reaching and terminal refractory glaucoma. RU patent 2707379. 2018 Sept. 27. (In Russ.)
11. Belikova E.I., Shvajlikova I.E. Method for surgical treatment of primary subcompensated open-angle glaucoma with the presence of a toxic-allergic reaction to hypotensive therapy. RU patent 2735065. 2020 Apr. 13. (In Russ.)
12. Sokolovskaya T.V., Malyugin B.E., Magaramov Dzh.A., Yashina V.N. Combined method of treating patients with primary open-angle glaucoma and complicated cataract. RU patent 2689015. 2018 May 17. (In Russ.)
13. Dzhashi B.G., Fokin V.P., Balalin S.V. Method of treating patients with complicated cataract and glaucoma with underlying pseudoexfoliation syndrome. RU patent 2695920. 2018 July 19. (In Russ.)
14. Avdeev R.V., Alexandrov A.S., Basinsky A.S., Blyum E.A., Brezhnev A.Yu. et al. Clinical multicenter study of trabeculectomy efficacy. National Journal glaucoma.2013; 12(2):53-60. (In Russ.)
15. Gusarevich A.A., Zavadski P.C., Kuroyedov A.V., Gazizova I.R., Zvereva O.G., Karimov U.R. et al. The correct choice of monotherapy with prostaglandin analogues/ prostamides at the start of treatment for newly diagnosed glaucoma (results of a multicenter study). National Journal glaucoma. 2020; 19(3):43-57. (In Russ.) doi.org/10.25700/NJG.2020.03.05
16. Petrov S.Yu., Volzhanin A.V. Trabeculectomy: history, terminology, technique. National Journal glaucoma.2017; 16(2):82-91. (In Russ.)
17. Glaukoma: klinika, diagnostika, lechenie: prakticheskoe posobie dlya vracha-terapevta i vracha obshchej praktiki [Glaucoma: clinic, diagnosis, treatment: a practical guide for a general practitioner] Eds by A.V. Kuroedov, Yu.I. Razhko, O.N. Onufriychuk, D.A. Baryshnikova. Moscow: Ophthalmology; 2020. 40 p. (In Russ.)
18. Bikbov M.M., Zajdullin I.S., Nazarov P.V., Khusnitdinov I.I. Method of treating glaucoma. RU patent 2581820. 2014 Oct. 13. (In Russ.)
19. Muldashev E.R., Galimova V.U., Musin U.K., Nurkhakimov R.Z. A method of surgical treatment of glaucoma with minimally invasive sponge drainage of the anterior chamber. RU patent 2533987. 2013 Feb. 26. (In Russ.)
20. Egorova E.V., Kozlova E.E., Eremenko I.L. Method of microinvasive nonpenetrating deep sclerotomy. RU patent 2548513. 2013 Sep. 16. (In Russ.)
21. Korchuganova E.A., Rumyantseva O.A. Method for surgical treatment of glaucoma by resection of sclera. RU patent 2587856. 2015 Mar. 04. (In Russ.)
22. Zhuravleva A.N., Sulejman E.A., Kiseleva O.A., Jakubova L.V. Method for surgical treatment of glaucoma. RU patent 2603295. 2015 Oct. 28. (In Russ.)
23. Mamikonyan V.R., Osipyan G.A., Petrov S.Yu. et al. Method for open-angle glaucoma surgery. RU patent 2610563. 2015 Dec. 16. (In Russ.)
24. Kiseleva O.A., Sulejman E.A., Bessmertnyj A.M. et al. Method of glaucoma surgical treatment. RU patent 2668702. 2018 Jan. 19. (In Russ.)
25. Kiseleva O.A., Suleiman E.A., Bessmertny A.M. et al. Method for surgical treatment of primary open-angle glaucoma. RU patent 2668703. 2018 Jan. 24. (In Russ.)
26. Erichev V.P. Refractory glaucoma: treatment patterns. Vestn oftalmol. 2000; 5:8-10. (In Russ.)
27. Ermolaev A.P., Usov A.V. Method of surgical treatment of refractory glaucoma at terminal stage. RU patent 2500367. 2012 Nov. 08. (In Russ.)
28. Kumar V., Frolov M.A., Shradka A.S. et al. Method of glaucoma surgical treatment. RU patent 2676967. 2017 May 31. (In Russ.)
29. Ovchinnikova A.V., Nasyrova I.M. Method surgical treatment of glaucoma developed against the background of iridocorneal endothelial syndrome. RU patent 2675967. 2018 Jan. 18. (In Russ.)
30. Kuroedov A.V., Ogorodnikovа V.Yu., Fomin N.E. The results of long-term monitoring of patients with primary open angle glaucoma after implantation of mini-shunt Ex-PRESS. Clinical Ophthalmology. 2015; (3):131-136. (In Russ.)
31. Kiseleva O.A., Zhuravleva A.N., Jakubova L.V., Sulejman E.A. Method for surgical treatment of glaucoma. RU patent 2582047. 2015 May 05. (In Russ.)
32. Kuznetsov S.L., Boldyreva I.A. Method for surgical management of openangle glaucoma. RU patent 2541057. 2013 Jan. 09. (In Russ.)
33. Kiseleva O.A., Bessmertnyj A.M., Zhuravleva A.N. et al. Method of glaucoma surgical treatment. RU patent 2644550. 2017 May 10. (In Russ.)
34. Alekseev I.B., Proshina O.I., Sidorova A.V. et al. Method for surgical management of open-angle glaucoma in patients with pseudophakia. RU patent 2642731. 2017 Apr. 13. (In Russ.)
35. Alekseev I.B., Proshina O.I., Sokolovskaya T.V. et al. Method for surgical management of open-angle glaucoma. RU patent 2662904. 2017 Sep. 21. (In Russ.)
36. Egorova E.V., Novikov S.V., Takhchidi E.K., Ignat'ev A.V. Drainage for surgical treatment of glaucoma. RU patent 2576815. 2015 Jan. 30. (In Russ.)
37. Khodzhaev N.S., Sidorova A.V.,Kolomejtsev M.N. et al. Drainage for glaucoma surgery. RU patent 2613435. 2015 Dec. 17. (In Russ.)
38. Germanova V.N., Karlova E.V., Zolotarev A.V. et al. Method for prevention of postoperative cicatrisation in surgical treatment of glaucoma. RU patent 2724854. 2020 Feb. 27. (In Russ.)
39. Germanova V.N., Korigodsky A.R., Zakharov I.D. et al. Method for the prevention of postoperative scarring during surgical treatment. RU patent 2018139597. 2020 May 12. (In Russ.)
40. Kiseleva O.A., Bessmertnyj A.M., Sulejman E.A. et al. Method of carrying out filtering bleb needling. RU patent 2675346. 2018 June 18. (In Russ.)
41. Ambartsumyan K.G., Rostomyan M.S. Method for prolonging the needling results of the scar-modified filtration pad. RU patent 2734050. 2019 Dec. 11. (In Russ.)
Review
For citations:
Razhko Yu.I., Glushnev I.A., Rebenok N.A., Kuroyedov A.V., Brezhnev A.Yu. Novel approaches to glaucoma treatment (review of patents). National Journal glaucoma. 2021;20(2):72-80. (In Russ.) https://doi.org/10.53432/2078-4104-2021-20-2-72-80
Views:
777
Email this article 