Clinic and functional state dynamic of deep sclerectomy with xenocollagen drainage implantation in patients with neovascular glaucoma

PURPOSE: The analysis of the results of deep sclerectomy with xenocollagen drainage implantation in patients with neovascular glaucoma during dynamic observation process. METHODS: The study included 80 patients (80 eyes) with neovascular glaucoma. All patients were divided into two groups depending on the surgical technique: group I (main group) included 40 patients after a deep sclerectomy with xenocollagen drainage implantation (DSE with XDI), group II (control group) - 40 patients after standard deep sclerectomy. All patients underwent a standard eye examination including visometry, perimetry, tonometry, tonography, biomicroscopy, gonioscopy, ophthalmoscopy, A-, B- scan («А/В 3D-OTI Scan 2000», Canada), ultrasound biomicroscopy («Paradigm Model P60™ UBM», USA). RESULTS: There was a significant difference in the persistence of post-operative hypotensive effect in the two studied groups. IOP decompensation rate in the control group exceed that in the study group (15 vs 3%, respectively) in long-term follow-up. Statistically significant positive changes in the visual functions were noted in the main group within 1 month after surgery, which remained stable during the 12 months of the observation period. The scarring of the filtration area was the main cause of glaucoma relapse in patients of the control group. CONCLUSION: According to the observation data, there was a statistically significant improvement in clinical and functional indicators in patients of the main group, which remained stable during late postoperative period, as compared to the control group. Using the modified operation technique with xenocollagen drainage implantation in the treatment of neovascular glaucoma promotes the stabilization of the clinical and functional results.

неоваскулярная глаукома, антиглаукоматозная операция, ксеноколлагеновый дренаж, neovascular glaucoma, glaucoma surgery, xenocollagen drainage

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