Возрастные изменения структуры и биомеханических свойств фиброзной оболочки глаза (обзор зарубежной литературы). Сообщение 1. Структурные изменения

Роговица и склера формируют фиброзную оболочку глаза, способную противостоять внешним и внутренним воздействиям и поддерживать форму глазного яблока. Функционирование данных оболочек связано с их структурными особенностями и биомеханическими свойствами, изменение которых с возрастом сказывается на способности выполнять защитную и опорную функции и является прямой или косвенной причиной ряда глазных болезней. Структурные изменения фиброзной оболочки глаза связаны в первую очередь с нарушением организации волокон коллагена, эластина и протеогликанов, которые составляют основу стромы роговицы и склеры. Происходит изменение организации фибриллярных компонентов и увеличение количества поперечных сшивок. Структурные изменения соединительной ткани глаза отражаются на ее функциональном состоянии, в первую очередь на вязкоупругих свойствах роговицы и склеры. Общей тенденцией возрастных изменений фиброзной оболочки глаза, по данным зарубежных исследователей, является увеличение жесткости и снижение вязкоэластических показателей.

роговица, склера, фиброзная оболочка, коллаген, эластин, протеогликаны, соединительная ткань, биомеханика, морфология, старение, cornea, sclera, fibrous tunic, collagen, elastin, proteoglycans, connective tissue, biomechanics, morphology, aging

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