Tonometric intraocular pressure in adult population: a population study
https://doi.org/10.25700/NJG.2020.02.05
Abstract
PURPOSE: To study the distribution of intraocular pressure (IOP) obtained by Maklakov tonometry in different age groups.
METHODS: The study evaluated Caucasians without glaucoma aged 45-75. The participants underwent Maklakov tonometry with a 10 g tonometer at 09:00-12:00 with subsequent imprint evaluation by means of NesterovEgorov scale, measurements of central corneal thickness (CCT) and visual acuity. All the participants were divided into 3 groups by age: Group 1 consisted of participants aged 45-55, Group 2 comprised the ones aged 56-65, Group 3 included patients aged 66-75.
RESULTS: In total 791 person were enrolled; 1 429 of 1 499 eyes (95.3%) were accepted into the study. IOP in Group I was 16.1±3.3 mmHg in Group 1; 16.3±3.3 in Group 2; 16.2±3.5 mmHg in Group 3. CCT in Group 1 was 545.7±14.6 μm; 545.3±15.4 μm in Group 2; 544.7±14.6 μm in Group 3. Visual acuity was 0.93±0.13 in Group 1; 0.89±0.15 in Group 2; 0.81±0.18 in Group 3. Average IOP in men was 16.4±3.3 mmHg, in women 16.5±3.3 mmHg. Age, vision acuity, CCT and IOP were within the normal distribution; IOP and CCT had no significant differences between the age groups. The measured parameters showed no significant intercorrelation. We found no significant difference between IOP in men and women.
CONCLUSION: In a healthy population CCT and IOP values fall within a normal distribution and do not change significantly with age. IOP does not depend on sex. Average IOP in the studied population is 16.2±3.4 mmHg, average CCT is 545.3±15.1 μm.
About the Authors
E. A. EgorovRussian Federation
Med.Sc.D., Professor, Head of the Ophthalmology Department
1 Ostrovitianov st., Moscow, 117997
S. Yu. Petrov
Russian Federation
Med.Sc.D., main research associate of Glaucoma Department
11A Rossolimo st., Moscow, 119021
V. V. Gorodnichy
Russian Federation
Ophthalmologist of the Ophthalmology Department of the Premorbid and Emergency Medical Center
8 A Bol’shaya Olen’ya st., Moscow, 107014
A. V. Kuroyedov
Russian Federation
Med.Sc.D., Professor Pirogov Russian National Research Medical University, Head of Ophthalmology Department P.V. Mandryka Central military clinical hospital of the Russian Defense Ministry
1 Ostrovitianov st., Moscow, 117997, 8 A Bol’shaya Olen’ya st., Moscow, 107014
V. N. Alekseev
Russian Federation
Med.Sc.D., Head of Ophthalmology Department
41 Kirochnaya st., Saint-Petersburg, 191015
A. N. Amirov
Russian Federation
Ph.D., Associate Professor of the Ophthalmology Department
36 Butlerova st., Kazan, Republic of Tatarstan, 420012
S. V. Balalin
Russian Federation
Med.Sc.D., Head of Research Department
80 Zemlyachki st., Volgograd, 400138
S. N. Basinskiy
Russian Federation
Med.Sc.D., Professor of Special Surgical Disciplines Department I.S. Turgenev Orel State University, CEO Professor S.N. Basinskiy Ophthalmological center
95 Komsomolskaya st., Orel, 3020269,
1 Krasnoarmeyskaya st., Orel, 3020269
M. M. Bikbov
Russian Federation
Med.Sc.D., Professor, Corresponding Member of the Academy of Sciences of the Republic of Bashkortostan, Director
90 Pushkin st., Ufa, 450008
T. K. Botabekova
Kazakhstan
Med.Sc.D., Professor, Corresponding Member of the Academy of Sciences of the Republic of Kazakhstan, Chairman of the board of directors
62 Zheltoksan, Almaty, 050000
A. Yu. Brezhnev
Russian Federation
Ph.D., Associate Professor of the Ophthalmology Department
42a Sadovaya st., Kursk, 305041
Z. F. Veselovskaya
Ukraine
Med.Sc.D., Professor, Corresponding Member of the Ukraine National Academy of Sciences, Head of the Ophthalmology Department12, Director13
N. V. Volkova
Russian Federation
Ph.D., Head of Science and Education Department Irkutsk Branch of S. Fyodorov Eye Microsurgery Federal State Institution, Associate professorIrkutsk State Medical Academy of Postgraduate Education, Irkutsk State Medical University
337 Lermontova st., Irkutsk, 664033,
100 Yubileiny, Irkutsk, 664049,
1 Krasnogo Vosstania st., Irkutsk, 664003
I. R. Gazizova
Russian Federation
Med.Sc.D., Head of Ophthalmology Department
12 Academician Pavlov st., Saint-Petersburg, 197376
V. U. Galimova
Russian Federation
Med.Sc.D., Professor of Ophthalmology Department
3 Lenina st., Ufa, Republic of Bashkortostan, 450008
O. G. Gusarevich
Belarus
Med.Sc.D., Professor of Ophthalmology Department
130 Nemirovich-Danchenko st., Novosibrsk, 630047
M. F. Jumova
Belarus
Ph.D., Associate Professor of the Department of Eye Diseases
30 Lenina st., Minsk, 220030
L. P. Dogadova
Russian Federation
Ph.D., Professor of the Ophthalmology Department
2 Ostriakova ave., Vladivostok, 690002
V. V. Egorov
Russian Federation
Med.Sc.D., Professor, Academician of Russian Academy of Natural Sciences, Main consultant The Khabarovsk branch of the S. Fyodorov Eye Microsurgery Federal State Institution, Head of the Ophthalmology Department The Postgraduate Institute for Public Health Workers
211 Tihookeanskaya st., Khabarovsk, 680033,
9 Krasnodarskaya st., Khabarovsk, 680009
V. P. Erichev
Russian Federation
Med.Sc.D., Professor, Head of Glaucoma Department
11A Rossolimo st., Moscow, 119021
N. V. Ivanova
Russian Federation
Med.Sc.D., Professor, Head of the Ophthalmology Department
5/7 Lenina blvd., Simferopol, 295051
T. A. Imshenetskaya
Belarus
Med.Sc.D., Professor, Head of the Ophthalmology Department
73 Uborevicha st., Minsk, 220096
T. G. Kamenskikh
Russian Federation
Med.Sc.D., Associate Professor, Head of the Eye Diseases Department
112 Bolshaya Kazachya st., Saratov, 410012
E. V. Karlova
Russian Federation
Ph.D., Head of Glaucoma Department
158 Novo-Sadovaya st., Samara, 443068
V. N. Kushnir
Moldova, Republic of
Med.Sc.D., Professor, Head of the Department of Eye Diseases and Optometry
165 Ștefan cel Mare, Chișinău, MD-2004
O. I. Lebedev
Russian Federation
Med.Sc.D., Professor, Head of Ophthalmology Department
60 Lermontov st., Omsk, 644024
L. N. Marchenko
Belarus
Med.Sc.D., Professor, Head of the Eye Diseases Department
69 Shevchenko st., Dushanbe, 734000
D. N. Sadykova
Tajikistan
Advisor to the Minister of Health and Social Protection of Population Ministry of Health and Social Protection of the Population of the Republic of Tajikistan, ophthalmologist of the Children’s Eye Department State institution National Medical Center «Shifobahsh» of the Republic of Tajikistan
69 Shevchenko st., Dushanbe, 734000,
59 I. Somoni ave., Dushanbe, 734064
N. A. Sobianin
Russian Federation
Ph.D., Head of the Ophthalmology Department
230 Permskaya st., Perm, 614068
V. V. Strakhov
Russian Federation
Med.Sc.D., Professor, Head of the Ophthalmology Department
5 Revolucionnaya st., Yaroslavl, 150000
V. V. Chernykh
Russian Federation
Med.Sc.D., Professor, Director
10 Kolhidskaya st., Novosibirsk, 630071
V. F. Ekgardt
Russian Federation
Med.Sc.D., Professor of Eye Diseases Department
64 Vorovsky st., Chelyabinsk, 454092
Yu. N. Yurieva
Russian Federation
Med.Sc.D., Professor, Deputy Director for Scientific Work Irkutsk Branch of S. Fyodorov Eye Microsurgery Federal State Institution, Professor of Ophthalmology Department Irkutsk State Medical Academy of Postgraduate Education, Irkutsk State Medical University
337 Lermontova st., Irkutsk, 664033,
100 Yubileiny, Irkutsk, Russian Federation, 664049,
1 Krasnogo Vosstania st., Irkutsk, 664003
References
1. Tham Y.C., Li X., Wong T.Y., Quigley H.A., Aung T., Cheng C.Y. Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. Ophthalmology. 2014; 121(11):2081-2090. doi:10.1016/j.ophtha.2014.05.013
2. Flaxman S.R., Bourne R.R.A., Resnikoff S., Ackland P., Braithwaite T., Cicinelli M.V., Das A., Jonas J.B., Keeffe J., Kempen J.H., Leasher J., Limburg H., Naidoo K., Pesudovs K., Silvester A., Stevens G.A., Tahhan N., Wong T.Y., Taylor H.R., Vision Loss Expert Group of the Global Burden of Disease S. Global causes of blindness and distance vision impairment 1990-2020: a systematic review and meta-analysis. Lancet Glob Health. 2017; 5(12):e1221-e1234. doi:10.1016/S2214-109X(17)30393-5
3. Sabanayagam C., Cheng C.Y. Global causes of vision loss in 2015: are we on track to achieve the Vision 2020 target? Lancet Glob Health. 2017; 5(12):e1164-e1165. doi:10.1016/S2214-109X(17)30412-6
4. Terminology and guidelines for glaucoma: European glaucoma society. 4th edition. Savona, Italy; 2014.
5. Nacional'noe rukovodstvo po glaukome [National guidelines for glaucoma], 3rd ed. Ed. by E.A. Egorov, Yu.S Astakhov, V.P. Erichev. Moscow: GEOTAR-Media Publ.; 2015. 456 p. (In Russ.).
6. Choquet H., Thai K.K., Yin J., Hoffmann T.J., Kvale M.N., Banda Y., Schaefer C., Risch N., Nair K.S., Melles R., Jorgenson E. A large multiethnic genome-wide association study identifies novel genetic loci for intraocular pressure. Nat Commun. 2017; 8(1):2108. doi:10.1038/s41467-017-01913-6
7. David R., Zangwill L., Stone D., Yassur Y. Epidemiology of intraocular pressure in a population screened for glaucoma. Br J Ophthalmol. 1987; 71(10):766-771. doi:10.1136/bjo.71.10.766
8. Fukuoka S., Aihara M., Iwase A., Araie M. Intraocular pressure in an ophthalmologically normal Japanese population. Acta Ophthalmol. 2008; 86(4):434-439. doi:10.1111/j.1600-0420.2007.01068.x
9. Vijaya L., George R., Arvind H., Ve Ramesh S., Baskaran M., Raju P., Asokan R., Velumuri L. Central corneal thickness in adult South Indians: the Chennai Glaucoma Study. Ophthalmology. 2010; 117(4):700- 704. doi:10.1016/j.ophtha.2009.09.025
10. Xu L., Li J., Zheng Y., Cui T., Zhu J., Ma K., Yang H., Ma B., Jonas J.B. Intraocular pressure in Northern China in an urban and rural population: the Beijing eye study. Am J Ophthalmol. 2005; 140(5):913-915. doi:10.1016/j.ajo.2005.04.050
11. Onishchenko A.L., Kolbasko A.V., Shirota M.A. Intraocular pressure in Tubalars-the indigenous population of the Altai Republic. Glaucoma. 2011; 4:49-51. (In Russ.).
12. Baboolal S.O., Smit D.P. South African Eye Study (SAES): ethnic differences in central corneal thickness and intraocular pressure. Eye (Lond). 2018; 32(4):749-756. doi:10.1038/eye.2017.291
13. Charaf W.M., Siplivy V.I. The reasons for late diagnosis and epidemiological features of glaucoma in the North-eastern region of the Arabian Peninsula. Natsional’nyi zhurnal glaukoma. 2015; 14(4): 44-50. (In Russ.).
14. Bikbov M.M., Kazakbaeva G.M., Zainullin R.M., Salavatova V.F., Gilmanshin T.R., Yakupova D.F., Uzianbaeva Y.V., Arslangareeva I.I., Panda-Jonas S., Mukhamadieva S.R., Khikmatullin R.I., Aminev S.K., Nuriev I.F., Zaynetdinov A.F., Jonas J.B. Intraocular pressure and its associations in a Russian population: The Ural Eye and Medical Study. Am J Ophthalmol. 2019; 204:130-139. doi:10.1016/j.ajo.2019.02.030
15. Klein B.E., Klein R., Linton K.L. Intraocular pressure in an American community. The Beaver Dam Eye Study. Invest Ophthalmol Vis Sci. 1992; 33(7):2224-2228.
16. Wu S.Y., Leske M.C. Associations with intraocular pressure in the Barbados Eye Study. Arch Ophthalmol. 1997; 115(12):1572-1576. doi:10.1001/archopht.1997.01100160742012
17. Lee M.K., Cho S.I., Kim H., Song Y.M., Lee K., Kim J.I., Kim D.M., Chung T.Y., Kim Y.S., Seo J.S., Ham D.I., Sung J. Epidemiologic characteristics of intraocular pressure in the Korean and Mongolian populations: the Healthy Twin and the GENDISCAN study. Ophthalmology. 2012; 119(3):450-457. doi:10.1016/j.ophtha.2011.09.016
18. Lin H.Y., Hsu W.M., Chou P., Liu C.J., Chou J.C., Tsai S.Y., Cheng C.Y. Intraocular pressure measured with a noncontact tonometer in an elderly Chinese population: the Shihpai Eye Study. Arch Ophthalmol. 2005; 123(3):381-386. doi:10.1001/archopht.123.3.381
19. Kalfa S.Yu. On the question of theory of tonometry with applanation tonometers. Russian Ophthalmological Journal. 1927; 6(10):1132- 1141. (In Russ.).
20. Nesterov A.P., Vurgaft M.B. Calibration tables for the Filatov - Kalf elastotonometer. Vestn oftalmol. 1972; 88(2):20-25. (In Russ.).
21. Vurgaft M.V. On the a calibration of Maklakov tonometers of different weight. Ophthalmology journal (USSR). 1965(6):443-448. (In Russ.).
22. Egorov E.A., Erichev V.P., Kuroedov A.V., Petrov S.Yu., Antonov A.A. Tonometric intraocular pressure reference values in healthy population. Natsional’nyi zhurnal glaukoma. 2018; 17(2):91-98. (In Russ.).
23. Vurdaft А.Е. On the precision of Polyak measuring scales in Maklakov tonometry. Natsional’nyi zhurnal glaukoma. 2017;16(4):11-22. (In Russ.).
24. Machekhin V.A., Lvov V.A. Regarding the comparability of the investigation outcomes of the true intraocular pressure according to the pneutonometer Reichert 7cr data and applanation tonometry by Maklakov. Vestnik TGU. 2015; 20(4):776-780. (In Russ.).
25. Chan M.P., Grossi C.M., Khawaja A.P., Yip J.L., Khaw K.T., Patel P.J., Khaw P.T., Morgan J.E., Vernon S.A., Foster P.J., UK Biobank Eye and Vision Consortium. Associations with Intraocular Pressure in a Large Cohort: Results from the UK Biobank. Ophthalmology. 2016; 123(4):771-782. doi:10.1016/j.ophtha.2015.11.031
26. Hoehn R., Mirshahi A., Hoffmann E.M., Kottler U.B., Wild P.S., Laubert-Reh D., Pfeiffer N. Distribution of intraocular pressure and its association with ocular features and cardiovascular risk factors: the Gutenberg Health Study. Ophthalmology. 2013; 120(5):961-968. doi:10.1016/j.ophtha.2012.10.031
27. Hashemi H., Kashi A.H., Fotouhi A., Mohammad K. Distribution of intraocular pressure in healthy Iranian individuals: the Tehran Eye Study. Br J Ophthalmol. 2005; 89(6):652-657. doi:10.1136/bjo.2004.058057
28. Hashemi H., Khabazkhoob M., Emamian M.H., Shariati M., Yekta A., Fotouhi A. Distribution of intraocular pressure and its determinants in an Iranian adult population. Int J Ophthalmol. 2016; 9(8):1207-1214. doi:10.18240/ijo.2016.08.19
29. Kim M.J., Park K.H., Kim C.Y., Jeoung J.W., Kim S.H. The distribution of intraocular pressure and associated systemic factors in a Korean population: the Korea National Health and Nutrition Examination Survey. Acta Ophthalmol. 2014; 92(7):e507-513. doi:10.1111/aos.12327
30. Khawaja A.P., Springelkamp H., Creuzot-Garcher C., Delcourt C., Hofman A., Hohn R., Iglesias A.I., Wolfs R.C., Korobelnik J.F., Silva R., Topouzis F., Williams K.M., Bron A.M., Buitendijk G.H., Cachulo M.D., Cougnard-Gregoire A., Dartigues J.F., Hammond C.J., Pfeiffer N., Salonikiou A., van Duijn C.M., Vingerling J.R., Luben R.N., Mirshahi A., Lamparter J., Klaver C.C., Jansonius N.M., Foster P.J., European Eye Epidemiology C. Associations with intraocular pressure across Europe: The European Eye Epidemiology (E(3)) Consortium. Eur J Epidemiol. 2016; 31(11):1101-1111. doi:10.1007/s10654-016-0191-1
31. Leske M.C., Connell A.M., Wu S.Y., Hyman L., Schachat A.P. Distribution of intraocular pressure. The Barbados Eye Study. Arch Ophthalmol. 1997; 115(8):1051-1057. doi:10.1001/archopht.1997.01100160221012
32. Wong T.T., Wong T.Y., Foster P.J., Crowston J.G., Fong C.W., Aung T., SiMES Study Group. The relationship of intraocular pressure with age, systolic blood pressure, and central corneal thickness in an asian population. Invest Ophthalmol Vis Sci. 2009; 50(9):4097-4102. doi:10.1167/iovs.08-2822
33. Pakravan M., Javadi M.A., Yazdani S., Ghahari E., Behroozi Z., Soleimanizad R., Moghimi S., Nilforoushan N., Zarei R., Eslami Y., Ghassami M., Ziaei H., Katibeh M., Tabesh H., Yaseri M. Distribution of intraocular pressure, central corneal thickness and vertical cup-todisc ratio in a healthy Iranian population: the Yazd Eye Study. Acta Ophthalmol. 2017; 95(2):e144-e151. doi:10.1111/aos.13231
34. Nangia V., Jonas J.B., Sinha A., Matin A., Kulkarni M. Central corneal thickness and its association with ocular and general parameters in Indians: the Central India Eye and Medical Study. Ophthalmology. 2010; 117(4):705-710. doi:10.1016/j.ophtha.2009.09.003
35. Zhang H., Xu L., Chen C., Jonas J.B. Central corneal thickness in adult Chinese. Association with ocular and general parameters. The Beijing Eye Study. Graefes Arch Clin Exp Ophthalmol. 2008; 246(4):587-592. doi:10.1007/s00417-007-0760-9
36. Maklakov A.N. More of ophthalmotonometry. Khirurgicheskaya letopis’. 1893; 4:1-11. (In Russ.).
37. Melnik L.S. On the norms of the elastotonometry curves. Journal of Ophthalmology (USSR). 1961; 16(4):221. (In Russ.).
38. Nesterov A.P., Cherkunov B.F. Elastotonometric examinations of the normal eyes. Collection of scientific articles of Kuybyshev Medical Institute. Kuybyshev; 1963: 97-99. (In Russ.).
39. Belorussov V.K. On the normal elastotonometric curves of people of different age categories. Journal of Ophthalmology (Ukraine). 1964; 19(5):326-331. (In Russ.).
40. Panina N.B. On the normal intraocular pressure. Glaucoma and other eye diseases. 1971: 7-12. (In Russ.).
41. Alekseev V.N., Egorov E.A., Martynova E.B. On the intraocular pressure levels distributon in the normal population. RMJ Clinical Ophthalmology. 2001; 2(2):38-40. (In Russ.).
42. Memarzadeh F., Ying-Lai M., Azen S.P., Varma R., Los Angeles Latino Eye Study G. Associations with intraocular pressure in Latinos: the Los Angeles Latino Eye Study. Am J Ophthalmol. 2008; 146(1):69-76. doi:10.1016/j.ajo.2008.03.015
43. Landers J., Henderson T., Craig J. Distribution and associations of intraocular pressure in indigenous Australians within central Australia: the Central Australian Ocular Health Study. Clin Exp Ophthalmol. 2011; 39(7):607-613. doi:10.1111/j.1442-9071.2011.02507.x
44. Han X., Niu Y., Guo X., Hu Y., Yan W., He M. Age-Related Changes of Intraocular Pressure in Elderly People in Southern China: Lingtou Eye Cohort Study. PLoS One. 2016; 11(3):e0151766. doi:10.1371/journal.pone.0151766
45. Cui Y., Yang X., Zhang G., Guo H., Zhang M., Zhang L., Zeng J., Liu Q., Zhang L., Meng Q. Intraocular Pressure in General and Diabetic Populations From Southern China: the Dongguan Eye Study. Invest Ophthalmol Vis Sci. 2019; 60(2):761-769. doi:10.1167/iovs.18-25247
Review
For citations:
Egorov E.A., Petrov S.Yu., Gorodnichy V.V., Kuroyedov A.V., Alekseev V.N., Amirov A.N., Balalin S.V., Basinskiy S.N., Bikbov M.M., Botabekova T.K., Brezhnev A.Yu., Veselovskaya Z.F., Volkova N.V., Gazizova I.R., Galimova V.U., Gusarevich O.G., Jumova M.F., Dogadova L.P., Egorov V.V., Erichev V.P., Ivanova N.V., Imshenetskaya T.A., Kamenskikh T.G., Karlova E.V., Kushnir V.N., Lebedev O.I., Marchenko L.N., Sadykova D.N., Sobianin N.A., Strakhov V.V., Chernykh V.V., Ekgardt V.F., Yurieva Yu.N. Tonometric intraocular pressure in adult population: a population study. National Journal glaucoma. 2020;19(2):39-50. (In Russ.) https://doi.org/10.25700/NJG.2020.02.05